Results 251 to 260 of about 268,817 (310)

V-H gene usage differs in germline and mutated B-cell chronic lymphocytic leukemia [PDF]

, 2003
Amlot, P, Duke, VM, Foroni, L, Gandini, D, Heelan, B, Hoffbrand, AV, Lin, K, Mehta, AB, Sherrington, PD   +8 more
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Chromosome abnormalities and gene rearrangements in malignant lymphoma.

, 1989
Nobuo Maseki, Yasuhiko Kaneko, Masaharu Sakurai   +2 more
openalex   +2 more sources

[A consistency comparison between next-generation sequencing and the FISH method for gene rearrangement detection in B-cell lymphomas]. [PDF]

Zhonghua Xue Ye Xue Za Zhi
Yan Z, Yao ZH, Yao SN, Zhao S, Wang HY, Chu JF, Xu YL, Zhang JY, Wei B, Zheng JW, Xia QX, Wu DY, Luo XF, Zhou WP, Liu YY.   +14 more
europepmc   +1 more source

T-cell receptor gamma gene rearrangement analysis of classic Hodgkin lymphoma using a BIOMED-2 assay: a paraffin-embedded tissue analysis of one hundred cases. [PDF]

J Clin Exp Hematop
Takata K, Miyata-Takata T, Nishikori A, Haratake T, Sato Y.   +4 more
europepmc   +1 more source

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The arrangement and rearrangement of antibody genes

Nature, 1978
Cloned segments of mouse chromosomal DNA provide direct evidence for the somatic rearrangement of kappa variable and constant region genes in antibody producing cells. This rearrangement apparently affects only one member of an allelic pair of light chain genes.
Seidman, J G, Leder, P
openaire   +3 more sources

Gene Rearrangements and T-Cell Lymphomas

Archives of Dermatology, 1993
Cutaneous T-cell lymphomas comprise a broad spectrum of neoplasia ranging from indolent to highly aggressive types. To determine subset lineage and malignant vs benign nature, morphologic analysis, immunophenotyping, and flow cytometry have been used. However, given the shortcomings of these methods, molecular genetic techniques, which take particular ...
Margaret H. Terhune, Kevin D. Cooper
openaire   +3 more sources

Antigen receptor gene rearrangement

Current Opinion in Immunology, 1998
Two specialized forms of site-directed double-strand (ds) DNA breakage and rejoining are part of the physiologic program of lymphocytes. One is recombination of the V, D and J gene sequences, termed V(D)J recombination, occurring during early B- and T-cell development, and the other is class-switch recombination occurring exclusively in mature B cells.
Michael R. Lieber, Robert B. West, Ulf Grawunder   +2 more
openaire   +3 more sources

Gene rearrangement and the generation of diversity [PDF]

Nature, 1982
THE eukaryotic genome has rececently begun to seem less stable, both in evolution1 and in ontogeny2, than many biologists had assumed. These trends prompted the Institute of Genetics to invite to its annual Spring meeting* speakers on six genetically labile systems: the MHC locus and the immunoglobulin genes of mammals, the genes encoding the surface ...
openaire   +2 more sources

Gene Rearrangements in Lymphoma

The American Journal of Dermatopathology, 1987
Clonality is regarded as an important diagnostic feature of B-cell lymphomas, but until recently the clonality of T-cell proliferations could not be directly determined. Elucidation of the genetic events in lymphocytic differentiation has led to the development of an assay for clonality in both B- and T-cell infiltrates.
Philip E. LeBoit, Tristram G. Parslow
openaire   +3 more sources