Results 261 to 270 of about 2,999,506 (308)

Regulation of nuclear and mitochondrial gene expression by contractile activity in skeletal muscle.

, 1986
R. Sanders Williams, Stanley Salmons, Eric A. Newsholme, Russel E. Kaufman, Jane Mellor   +4 more
openalex   +1 more source

Understanding and measuring mechanical signals in the tumor stroma

FEBS Open Bio, EarlyView.
This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz, Chiara Cimmino, Maurizio Ventre, Alessandra Cambi   +3 more
wiley   +1 more source

From homogeneity to heterogeneity: Refining stochastic simulations of gene regulation. [PDF]

Comput Struct Biotechnol J
Chae SJ, Shin S, Lee K, Lee S, Kim JK.
europepmc   +1 more source

Bioengineering facets of the tumor microenvironment in 3D tumor models: insights into cellular, biophysical and biochemical interactions

FEBS Open Bio, EarlyView.
The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik, Deniz Bakkalci, Alexander J. MacRobert, Umber Cheema   +3 more
wiley   +1 more source

Possible role of human ribonuclease dicer in the regulation of R loops

FEBS Open Bio, EarlyView.
R loops play an important role in regulating key cellular processes such as replication, transcription, centromere stabilization, or control of telomere length. However, the unscheduled accumulation of R loops can cause many diseases, including cancer, and neurodegenerative or inflammatory disorders. Interestingly, accumulating data indicate a possible
Klaudia Wojcik, Paulina Krzeminska, Anna Kurzynska‐Kokorniak   +2 more
wiley   +1 more source

Maternal diabetes disrupts early corticogenesis through altered mitotic gene regulation: a transcriptomic analysis. [PDF]

Front Endocrinol (Lausanne)
Valle-Bautista R, de la Merced-García DS, Díaz-Piña DA, Díaz NF, Ávila-González D, Molina-Hernández A.   +5 more
europepmc   +1 more source

Long non‐coding RNAs as therapeutic targets in head and neck squamous cell carcinoma and clinical application

FEBS Open Bio, EarlyView.
Long non‐coding RNAs (lncRNAs) occupy an abundant fraction of the eukaryotic transcriptome and an emerging area in cancer research. Regulation by lncRNAs is based on their subcellular localization in HNSCC. This cartoon shows the various functions of lncRNAs in HNSCC discussed in this review.
Ellen T. Tran, Ruchi A. Patel, Amogh Chariyamane, Ratna B. Ray   +3 more
wiley   +1 more source

Flexibility and sensitivity in gene regulation out of equilibrium. [PDF]

Proc Natl Acad Sci U S A
Mahdavi SD, Salmon GL, Daghlian P, Garcia HG, Phillips R.   +4 more
europepmc   +1 more source

The role of circular RNAs in regulating cytokine signaling in cancer

FEBS Open Bio, EarlyView.
Cytokines present in the tumor microenvironment fuel cancer development. Aberrant expression of circRNAs contributes to cancer progression. Cytokines are involved in regulating circRNA biogenesis. Furthermore, aberrantly expressed circRNAs regulate the expression of ligands, receptors, and downstream effectors involved in cytokine signaling to promote ...
Vandana Joshi, Swati, Amit Mishra, Amaresh Panda, Vivek Sharma   +4 more
wiley   +1 more source

Spatiotemporal transcriptomics reveals key gene regulation for grain yield and quality in wheat. [PDF]

Genome Biol
Li X, Wan Y, Wang D, Li X, Wu J, Xiao J, Chen K, Han X, Chen Y.   +8 more
europepmc   +1 more source