Results 171 to 180 of about 8,163,121 (296)

Integrated DNA Copy Number and Gene Expression Regulatory Network Analysis of Non-small Cell Lung Cancer Metastasis

Cancer Informatics, 2014
Seyed M. Iranmanesh, Nancy L. Guo
doaj  

Identification of Gene Regulatory Network for Nitrogen-Promoted Tiller Regrowth in Perennial Rice. [PDF]

Rice (N Y)
Lu Y, Huang G, Qi Z, Zhang Y, Liu F, Shao L, Zhang S, Hu F, Lei GJ.   +8 more
europepmc   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

TLR4 and RB1 as the Identified Lactate-Related Genes to Predict the Diagnostic Performance, Gene Regulatory Network, and Targeting Drugs in Depression. [PDF]

Hum Mutat
Ding F, Chen J, Wu J, Bian Q.
europepmc   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

Gene regulatory network analysis identifies dysregulation of hypoxia pathways as contributing to glioblastoma treatment resistance in females. [PDF]

Biol Sex Differ
Adebari T, Fanfani V, Guebila MB, DeConti D, Shutta KH, Lopes-Ramos CM, Hsu L, DeMeo DL, Quackenbush J, Eicher T.   +9 more
europepmc   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

TBL1X/TBL1XR1 govern β-cell identity through a PAX6-containing gene regulatory network. [PDF]

Nat Commun
Walth-Hummel AA, Jouffe C, Weber P, Motzler K, Geppert J, Sterr M, Gan W, Szczerbinska I, König AC, Hauck SM, Terron-Exposito R, Hass D, Wang C, Dyar KA, Lyon JG, Lickert H, Ämmälä C, Herzig S, Ashcroft FM, Bakhti M, MacDonald PE, Rohm M.   +21 more
europepmc   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Expanding the fly eye gene regulatory network: From Drosophila to the hoverfly Episyrphus balteatus. [PDF]

PLoS Genet
Navarro T, Torres J, Sáez-Moreno R, Guerrero G, Almudí I, Iannini A, Figueras J, Wotton K, Aerts S, Casares F.   +9 more
europepmc   +1 more source