Results 131 to 140 of about 1,824,389 (266)
Corrigendum: Optimized riboswitch-regulated AAV vector for VEGF-B gene therapy
Frontiers in Medicine, 2023 Reetta A. E. Eriksson +16 more
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Active learning for efficient discovery of optimal gene combinations in the combinatorial perturbation space [PDF]
arXivThe advancement of novel combinatorial CRISPR screening technologies enables the identification of synergistic gene combinations on a large scale. This is crucial for developing novel and effective combination therapies, but the combinatorial space makes exhaustive experimentation infeasible.
arxiv
In vivo manipulation of interleukin-2 expression by a retroviral tetracycline (tet)-regulated system [PDF]
, 2006 We have used the tetracycline (tet)-regulated system as described previously to evaluate the applicability of controlled gene expression in cancer gene therapy. As a model gene, we used the human interleukin-2 (IL-2) gene, which has been placed under the
Pitzer, Claudia +4 more
core
Possibilities of gene therapy for treatment and prevention of mass pathologies [PDF]
, 1990 В. А. Кордюм
openalex +1 more source
scGSDR: Harnessing Gene Semantics for Single-Cell Pharmacological Profiling [PDF]
arXivThe rise of single-cell sequencing technologies has revolutionized the exploration of drug resistance, revealing the crucial role of cellular heterogeneity in advancing precision medicine. By building computational models from existing single-cell drug response data, we can rapidly annotate cellular responses to drugs in subsequent trials. To this end,
arxiv
NIH seeks bids for vector centres for gene therapy [PDF]
, 1994 Helen Gavaghan
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Combining Transfer of TTF-1 and Pax-8 Gene: a Potential Strategy to Promote Radioiodine Therapy of Thyroid Carcinoma [PDF]
, 2011 Cotransfer of TTF-1 and Pax-8 gene to tumor cells, resulting in the reexpression of iodide metabolism-associated proteins, such as sodium iodide symporter (NIS), thyroglobulin (Tg), thyroperoxidase (TPO), offers the possibility of radioiodine therapy to ...
Anren Kuang +4 more
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Adeno-associated virus as a delivery vector for gene therapy of human diseases
Signal Transduction and Targeted TherapyAdeno-associated virus (AAV) has emerged as a pivotal delivery tool in clinical gene therapy owing to its minimal pathogenicity and ability to establish long-term gene expression in different tissues.
Jiang-Hui Wang +4 more
doaj +1 more source