Results 141 to 150 of about 1,824,389 (266)
Survey and Improvement Strategies for Gene Prioritization with Large Language Models [PDF]
arXivRare diseases are challenging to diagnose due to limited patient data and genetic diversity. Despite advances in variant prioritization, many cases remain undiagnosed. While large language models (LLMs) have performed well in medical exams, their effectiveness in diagnosing rare genetic diseases has not been assessed.
arxiv
Comparison of PCR-based restriction length polymorphism analysis of urease genes with rRNA gene profiling for monitoring Helicobacter pylori infections in patients on triple therapy [PDF]
, 1994 Robert J. Owen +4 more
openalex +1 more source
Drugs of Today, 2000 Gene therapy was initially thought of as a means to correct single gene defects in hereditary disease. Since then, cancer has become the most important indication for gene therapy in clinical trials. In the foreseeable future, the best way to achieve reasonable intratumoral concentrations of a transgene with available vectors will be direct ...
openaire +6 more sources
Cytokine therapy with gene-transfected cells: single injection of irradiated granulocyte-macrophage colony-stimulating factor-transduced cells accelerates hematopoietic recovery after cytotoxic chemotherapy in mice [PDF]
, 1994 F.M. Rosenthal +8 more
openalex +1 more source
Liver fibrosis negatively impacts in vivo gene transfer to murine hepatocytes
Nature CommunicationsLiver fibrosis occurs in several genetic and acquired disease conditions, leading to alterations of the tissue and metabolism, which may adversely affect viral vector-mediated gene therapy.
Chiara Simoni +12 more
doaj +1 more source
Breast cancer gene therapy: transgenic immunotherapy [PDF]
, 1994 Ning Su +3 more
openalex +1 more source
Development of Gene Therapy for Immunodeficiency: Adenosine Deaminase Deficiency [PDF]
, 1993 R. Michael Blaese
openalex +1 more source