Results 71 to 80 of about 1,204,526 (212)

Gene therapy [PDF]

Nature, 1992
openaire   +2 more sources

Gene therapy with IL-12 induced enhanced anti-tumor activity in fibrosarcoma mouse model [PDF]

, 2016
Saiedeh Razi Soofiyani, Tohid Kazemi, Farzaneh Lotfipour, Akbar Mohammad Hosseini, Dariush Shanehbandi, Somayeh Hallaj‐Nezhadi, Behzad Baradaran   +6 more
openalex   +1 more source

Discovering human cell‐compatible gene therapy virus variants via optimized screening in mouse models

, 2023
Moyu Dai, Ning Yang, Kai Xu, Jingwen Zhang, Xueke Li, Ying Zhang, Wei Li   +6 more
openalex   +1 more source

Adeno-associated virus as a delivery vector for gene therapy of human diseases

Signal Transduction and Targeted Therapy
Adeno-associated virus (AAV) has emerged as a pivotal delivery tool in clinical gene therapy owing to its minimal pathogenicity and ability to establish long-term gene expression in different tissues.
Jiang-Hui Wang, Dominic J. Gessler, Wei Zhan, Thomas L. Gallagher, Guangping Gao   +4 more
doaj   +1 more source

Safety and improved efficacy signals following gene therapy in childhood blindness caused by GUCY2D mutations [PDF]

, 2021
Samuel G. Jacobson, Artur V. Cideciyan, Allen C. Ho, Igor V. Peshenko, Alexandra V. Garafalo, Alejandro J. Román, Alexander Sumaroka, Vivian Wu, Arun K. Krishnan, Rebecca Sheplock, Sanford L. Boye, Bee-Lin Cheang, Vanessa Davidson, Catherine R. O’Riordan, Alexander M. Dizhoor, Sanford L. Boye   +15 more
openalex   +1 more source

Divergent on-target off-tumor effects by CAR T and CAR NK cells suggest different efficacy and safety of cell therapies

OncoImmunology
CAR-based cell therapies have shown clinical success in treating various cancers, with CAR T cell therapies entering the clinical route and CAR NK cell therapies being evaluated in early-stage clinical trials.
Katharina Schindler-Wnek, Anika Stahringer, Nadine Heimer, Ulrike Koehl, Stephan Fricke, Dominik Schmiedel   +5 more
doaj   +1 more source

Europe's First Gene Therapy [PDF]

, 1992
Angiola Bono
openalex   +1 more source

Normalization of wound healing and stem cell marker patterns in organ-cultured human diabetic corneas by gene therapy of limbal cells

, 2014
Mehrnoosh Saghizadeh, Christian M Dib, William J. Brunken, Alexander V. Ljubimov   +3 more
openalex   +1 more source

Current Trends in Viral Gene Therapy for Human Orthopaedic Regenerative Medicine

, 2019
Jagadeesh K. Venkatesan, Ana Rey‐Rico, Magali Cucchiarini   +2 more
openalex   +2 more sources

Liver fibrosis negatively impacts in vivo gene transfer to murine hepatocytes

Nature Communications
Liver fibrosis occurs in several genetic and acquired disease conditions, leading to alterations of the tissue and metabolism, which may adversely affect viral vector-mediated gene therapy.
Chiara Simoni, Justine Nozi, Francesco Starinieri, Tiziana La Bella, Elisabetta Manta, Camilla Negri, Mauro Biffi, Rossana Norata, Martina Rocchi, Francesca Sanvito, Giuseppe Ronzitti, Elena Barbon, Alessio Cantore   +12 more
doaj   +1 more source