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Regulation of the immunoglobulin gene transcription
Biochimie, 1990The transcription of the immunoglobulin heavy (IGH), kappa (IGK) and lambda (IGL) chain genes is coordinate and B lymphocyte specific. This expression of the immunoglobulin genes is under the control of regulatory elements: the promoters located 5' of each variable (V) gene and the enhancers located between the joining and constant genes in the IGH and
G, Lefranc, M P, Lefranc
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A Transcriptional Approach to Gene Clustering
2005 IEEE Symposium on Computational Intelligence in Bioinformatics and Computational Biology, 2005We present an integrative method for clustering coregulated genes and elucidating their underlying regulatory mechanisms. We use multi-state partition functions and thermodynamic models to derive six distinct correlation classes that correspond to various Protein-Protein and Protein-DNA interactions.
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In Vitro Transcription of Adenovirus Genes
1983Before the development of recombinant DNA technology, DNA tumor vi–ruses provided a convenient source of DNA for analysis of a limited number of genes in eukaryotic cells. The virus can be purified in large amounts and the DNA extracted from the virions is free of cellular DNA sequences.
R, Weinmann +4 more
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Transcriptional Regulation of Complement Genes
Annual Review of Immunology, 1995Complement is a major effector system of host defense against invading pathogens. The recently completed cloning and structural characterization of almost all complement genes has allowed investigation of their regulation at the molecular level. Transcription of most complement genes is accelerated during the acute-phase response that follows tissue ...
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Regulation of ribosomal RNA gene copy number, transcription and nucleolus organization in eukaryotes
Nature Reviews Molecular Cell Biology, 2023Christoph Engel +2 more
exaly

