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Gene transcription in HIV infection

Microbes and Infection, 2003
Transcription from the HIV genome is regulated by the 5' long-terminal-repeat viral promoter as well as regulatory proteins, especially Tat and Rev. Both the promoter activity and the function of regulatory proteins require the activity of cellular components, thus the virus remains highly dependent on the metabolic state of the cell.
Yuntao, Wu, Jon W, Marsh
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Similarity of Transcription Profiles for Genes in Gene Sets

2011
In gene set focused knowledge-based analysis we assume that genes from the same functional gene set have similar transcription profiles. We compared the distributions of similarity scores of gene transcription profiles between genes from the same gene sets and genes chosen at random.
Marko Toplak, Tomaz Curk, Blaz Zupan
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Transcriptional regulation of the survivin gene

Molecular Biology Reports, 2013
Survivin, a small member of the inhibitors of the apoptosis protein family, is highly deregulated in cancer. It is weakly expressed in normal tissues but very strongly expressed in malignant lesions. Survivin is involved in cell-cycle progression, especially in the G2/M transition, and has anti-apoptotic activity, which correlates with its strong ...
Romain, Boidot   +2 more
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Regulation of Immunoglobulin Gene Transcription

1992
Analysis of the immunoglobulin gene suggests that their expression is controlled through the combinatorial action of tissue- and stage-specific factors (OTF-2, TF-microB, NF-kappa B), as well as more widely expressed E motif-binding factors such as E47/E12.
B, Nelsen, R, Sen
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On the ontogeny of cardiac gene transcripts

Mechanisms of Ageing and Development, 1994
As a prerequisite to investigating the specification and differentiation of cardiac tissue in vitro, the ontogeny of a number of putative cardiac-specific, and striated muscle-specific gene transcripts has been studied. The probes used include cDNAs of alpha-actins, myosin heavy chains, myosin light chains, alpha-tropomyosin, troponin-T and atrial ...
W G, Murrell   +3 more
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Gene Transcription

1993
Abstract Understanding the mechanisms and control of gene transcription is one of the central goals for a large proportion of molecular biologists currently involved in research. This book concentrates on RNA polymerase II transcription of eukaryotic protein-coding systems. Many of the approaches and techniques described apply equally
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Gene transcription in filamentous cyanobacteria

Microbiology, 1994
Cyanobacteria are probably the most diverse group of prokaryotes in the number of species, type of habitats, morphology and physiological properties. Their common feature is 0,-evolving photosynthesis, performed by mechanisms similar to those of algae and higher plants.
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Effects of Insulin on Gene Transcription

Annual Review of Physiology, 1989
for these changes in mRNA concentration. The steady-state concentration of a messenger RNA is determined by a sequence of events that includes initiation of transcription by RNA polymerase II, elongation of the trans cr ipt , termina­ tion of transcription, mRNA capping, polyadenylation, splicing, transport to the cytoplasm, and eventual degradation ...
M H, Meisler, G, Howard
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Transcriptional Control of Cytokine Genes

International Reviews of Immunology, 1998
With antigen stimulation, cytokine genes are coordinately expressed in T cells. However, the optimal signals or helper T cell subset specificity for each cytokine gene expression differ. Mechanisms probably exist that transmit extracellular signals into the nucleus, thereby coordinately turning on and off transcriptional machinery in a signal-specific ...
L, Tsuruta, N, Arai, K, Arai
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Control of transcription of the globin gene

Journal of Cellular Physiology, 1975
This report provides a more rigorous proof of previous findings that the RNA transcribed in vitro from the chromatins of different organs shows different sequence specificities. Here the particular case of the globin gene is considered for a comparison of embryonic mouse liver chromatin and mouse brain chromatin using the reverse transcriptase cDNA ...
R S, Gilmour   +3 more
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