Results 111 to 120 of about 1,625,963 (355)
Latest Update on Outer Membrane Vesicles and Their Role in Horizontal Gene Transfer: A Mini-Review [PDF]
, 2023 Beatrice Marinacci +4 more
openalex +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Inferring Horizontal Gene Transfer
PLOS Computational Biology, 2015 PLoS Computational Biology, 11 (5)
Ravenhall, M +3 more
openaire +7 more sources
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Novel T cells with improved in vivo anti-tumor activity generated by RNA electroporation
Protein & Cell, 2017 The generation of T cells with maximal anti-tumor activities will significantly impact the field of T-cell-based adoptive immunotherapy. In this report, we found that OKT3/IL-2-stimulated T cells were phenotypically more heterogeneous, with enhanced anti-
Xiaojun Liu +7 more
doaj +1 more source
Removal of Antibiotic Resistance Genes in an Anaerobic Membrane Bioreactor Treating Primary Clarifier Effluent at 20 °C [PDF]
, 2018 Anaerobic membrane bioreactors (AnMBR) play a key role in future plans for sustainable wastewater treatment and resource recovery because they have no energy-intensive oxygen transfer requirements and can produce biomethane for renewable energy.
Carey, Daniel Elliott +8 more
core +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
Antibiotic resistance via the food chain: Fact or fiction?
South African Journal of Science, 2010 The mechanisms that bacteria use to acquire additional genetic material, including genes coding for antibiotic resistance, are principally the secondary pathways that have been described as transformation and conjugation pathways.
Linda Bester, Sabiha Essack
doaj
Herpes Simplex Virus Vectors for Gene Transfer to the Central Nervous System
Diseases, 2018 Neurodegenerative diseases (NDs) have a profound impact on human health worldwide and their incidence is predicted to increase as the population ages. ND severely limits the quality of life and leads to early death.
Sara Artusi +4 more
doaj +1 more source