Results 261 to 270 of about 1,625,963 (355)

Repressive Cytosine Methylation is a Marker of Viral Gene Transfer Across Divergent Eukaryotes. [PDF]

Mol Biol Evol
Sarre LA, Gastellou Peralta GA, Romero Charria P, Ovchinnikov V, de Mendoza A.   +4 more
europepmc   +1 more source

Hydrodynamic gene transfer of alpha-galactosidase (GLA) in the GLA knockout mouse partially reverses biochemical deficits [PDF]

, 2012
Ali Mohamed Alshabi, Regis R. Vollmer, Michael J. Passineau, Maggie Folan   +3 more
openalex  

SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1

FEBS Open Bio, EarlyView.
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl, Khawar Amin, Lydia Gabriel, Nils Hampel, Afshin Iram, Julia Hesse, Constanze Wiek, Jasmin Thuy Vy Nguyen, Helmut Hanenberg, Jürgen Scheller, M. Reza Ahmadian, Björn Stork, Doreen M. Floss, Roland P. Piekorz   +13 more
wiley   +1 more source

Invasion dynamics of antimicrobial-resistant E. coli in river biofilms: impacts on the resistome, microbiomes, and horizontal gene transfer

Gionchetta G, Lee J, Hansen O, Beck K, Bürgmann H.   +4 more
europepmc   +1 more source

The complete mitochondrial genome of Sinojackia microcarpa: evolutionary insights and gene transfer. [PDF]

BMC Genomics
Zhong T, Huang S, Liu R, Zhuo J, Lu H, Gan C, Fu J, Qian Q.   +7 more
europepmc   +1 more source

Reviewer #1 (Public Review): Human HPSE2 gene transfer ameliorates bladder pathophysiology in a mutant mouse model of urofacial syndrome

Filipa M. Lopes, Céline Grenier, Benjamin W. Jarvis, Sara Al Mahdy, Adrian Lène-McKay, Alison M. Gurney, William G. Newman, Simon N. Waddington, Adrian S. Woolf, Neil Roberts   +9 more
openalex   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

Benchmarking pangenome dynamics and horizontal gene transfer in <i>Mycobacterium marinum</i> evolution. [PDF]

Front Microbiol
Shahed K, Islam SI, Sangsawad P, Jung WK, Permpoonpattana P, Linh NV.   +5 more
europepmc   +1 more source

The eukaryotic horizontal gene transfer dataset a compendium

James Spaulding, Janna L. Fierst
openalex   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source