Results 271 to 280 of about 5,395,678 (315)

Gene Transfer by Adenovectors

Blood, 1999
C LINICAL GENE THERAPY is going through an uncomfortable adolescence. Many observers have already been disappointed by the lack of clear-cut successes with this strategy. To this sense of frustration has now been added a feeling of dismay because of the death of an 18-year-old with ...
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Gene transfer by electroporation

Molecular Biotechnology, 1997
Electroporation of cells in the presence of DNA is widely used for the introduction of transgenes either stably or transiently into bacterial, fungal, animal, and plant cells. A review of the literature shows that electroporation parameters are often reported in an incomplete or incorrect manner, forcing researchers to rely too much on a purely ...
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Gene transfer into the nervous system

Molecular Neurobiology, 1987
Gene transfer into the cells of the nervous system has the potential to provide interesting information for many fields of the neurosciences, including neurochemistry, neurophysiology, developmental neurobiology, molecular neurobiology and neuropathology, and perhaps may even to contribute to the ongoing debate between psychologists and neurobiologists
X O, Breakefield, A I, Geller
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Gene Transfer: Conjugation

2014
Conjugation is a gene transfer process in which a recipient bacterium receives DNA from a donor bacterium by cell-to-cell contact through conjugative pili. Conjugation is mediated by certain plasmids or transposons. Here, we describe plasmid conjugation.
Sana, Thibault G, Laubier, Aurélie, Bleves, Sophie   +2 more
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Mammalian Gene Transfer and Gene Expression

1986
It has long been the desire of molecular biologists to be able to study the regulation of expression of specific mammalian genes. With the advent of recombinant DNA technology and the availability of specific cloned genes, several new approaches to these studies have emerged.
T E, Wagner, X Z, Chen, W B, Hayes
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Direct gene transfer to protoplasts: Fate of the transferred genes

Developmental Genetics, 1990
AbstractDirect gene transfer to protoplasts is one of several methods developed for the production of transgenic plants. This method utilizes the efficient uptake of DNA from the surrounding medium by protoplasts (cell wall‐less plant cells). Where a suitable protoplast system exists large numbers of transformant clones can be efficiently produced and ...
Michael W. Saul, Ingo Potrykus
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Novel Gene Transfer Systems: Intelligent Gene Transfer Vectors for Gene Medicines

Current Topics in Medicinal Chemistry, 2012
Drug delivery systems for gene transfer are called 'vectors'. These systems were originally invented as a delivery system for the transfection in vitro or in vivo. Several vectors are then developed for clinical use of gene medicines and currently some of them are approved as animal drugs.
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Gene Transfer in Fungi

1985
Publisher Summary This chapter reviews data regarding the nature of evidence for gene transfer in fungi and the characterization of the transformants, and discuss the use of gene transfer as a genetic system to seek answers to several questions concerning the regulatory control and other basic mechanisms of eukaryotes. Fungi offer a unique system for
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Gene Transfer: Transduction

2014
Bacteriophages able to propagate on Pseudomonas strains are very common and can be easily isolated from natural environments or lysogenic strains. The development of transducing systems has allowed bacterial geneticists to perform chromosome analyses and mutation mapping.
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Elevated rates of horizontal gene transfer in the industrialized human microbiome

Cell, 2021
B Jesse Shapiro, Mathilde Poyet, Jenni Lehtimäki   +2 more
exaly