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Tissue Engineering, 1995
The cardiovascular system is a promising site for gene delivery because of its large surface area and direct contact with the blood stream. Gene transfer into vascular cells by adenoviral and retroviral vectors or liposomes has been demonstrated in several cell types and animal models.
A D, Ouellette, K K, Wu, A G, Mikos
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The cardiovascular system is a promising site for gene delivery because of its large surface area and direct contact with the blood stream. Gene transfer into vascular cells by adenoviral and retroviral vectors or liposomes has been demonstrated in several cell types and animal models.
A D, Ouellette, K K, Wu, A G, Mikos
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2014
Conjugation is a gene transfer process in which a recipient bacterium receives DNA from a donor bacterium by cell-to-cell contact through conjugative pili. Conjugation is mediated by certain plasmids or transposons. Here, we describe plasmid conjugation.
Sana, Thibault G +2 more
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Conjugation is a gene transfer process in which a recipient bacterium receives DNA from a donor bacterium by cell-to-cell contact through conjugative pili. Conjugation is mediated by certain plasmids or transposons. Here, we describe plasmid conjugation.
Sana, Thibault G +2 more
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Current Opinion in Lipidology, 1997
Vascular gene transfer may be useful for the treatment of several cardiovascular diseases. It can also be used as an experimental tool to test the effects of various genes in a local vascular compartment. Promising therapeutic effects have been obtained in animal models of restenosis with the transfer of vascular endothelial growth factor, nitric oxide
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Vascular gene transfer may be useful for the treatment of several cardiovascular diseases. It can also be used as an experimental tool to test the effects of various genes in a local vascular compartment. Promising therapeutic effects have been obtained in animal models of restenosis with the transfer of vascular endothelial growth factor, nitric oxide
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Novel Gene Transfer Systems: Intelligent Gene Transfer Vectors for Gene Medicines
Current Topics in Medicinal Chemistry, 2012Drug delivery systems for gene transfer are called 'vectors'. These systems were originally invented as a delivery system for the transfection in vitro or in vivo. Several vectors are then developed for clinical use of gene medicines and currently some of them are approved as animal drugs.
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2009
Membrane electroporation (MEP) uses short high-voltage pulses to render cell membranes transiently porous and therewith permeable to otherwise impermeable substances. This technique was first described, in vitro, by Neumann in 1982. In vivo, this method is restricted to solid tissues accessible to the electrodes used to apply the electric field pulses.
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Membrane electroporation (MEP) uses short high-voltage pulses to render cell membranes transiently porous and therewith permeable to otherwise impermeable substances. This technique was first described, in vitro, by Neumann in 1982. In vivo, this method is restricted to solid tissues accessible to the electrodes used to apply the electric field pulses.
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2014
Bacteriophages able to propagate on Pseudomonas strains are very common and can be easily isolated from natural environments or lysogenic strains. The development of transducing systems has allowed bacterial geneticists to perform chromosome analyses and mutation mapping.
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Bacteriophages able to propagate on Pseudomonas strains are very common and can be easily isolated from natural environments or lysogenic strains. The development of transducing systems has allowed bacterial geneticists to perform chromosome analyses and mutation mapping.
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Gene Co-Inheritance and Gene Transfer
Science, 2007Functional transfer of mitochondrial genes to the nucleus is very common in some taxa but entirely lacking in others. Current evolutionary theories to account for this variation predict that outcrossing, which allows escape from Muller's ratchet and faster spread of beneficial mutations, should favor gene transfer. We find that functional gene transfer
Yaniv, Brandvain +2 more
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Horizontal gene transfer and adaptive evolution in bacteria
Nature Reviews Microbiology, 2021Brian J. Arnold, I-Ting Huang, W. Hanage
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Examining horizontal gene transfer in microbial communities
Nature Reviews Microbiology, 2021I. Brito
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Reproductive tract gene transfer
Fertility and Sterility, 2003Gene therapy is a rapidly evolving novel treatment for human disease. This review discusses the latest development in gene transfer technology and its potential use in the female reproductive tract.A comprehensive search using the MEDLINE database was performed to review current, innovative trends in gene transfer technology.
Gaurang S, Daftary, Hugh S, Taylor
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