Results 351 to 360 of about 10,802,441 (400)
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2009
Membrane electroporation (MEP) uses short high-voltage pulses to render cell membranes transiently porous and therewith permeable to otherwise impermeable substances. This technique was first described, in vitro, by Neumann in 1982. In vivo, this method is restricted to solid tissues accessible to the electrodes used to apply the electric field pulses.
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Membrane electroporation (MEP) uses short high-voltage pulses to render cell membranes transiently porous and therewith permeable to otherwise impermeable substances. This technique was first described, in vitro, by Neumann in 1982. In vivo, this method is restricted to solid tissues accessible to the electrodes used to apply the electric field pulses.
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Horizontal gene transfer in eukaryotic plant pathogens.
Annual Review of Phytopathology, 2014Gene transfer has been identified as a prevalent and pervasive phenomenon and an important source of genomic innovation in bacteria. The role of gene transfer in microbial eukaryotes seems to be of a reduced magnitude but in some cases can drive ...
D. Soanes, T. Richards
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Science, 1992
Direct in situ introduction of exogenous genes into proliferating tumors could provide an effective therapeutic approach for treatment of localized tumors. Rats with a cerebral glioma were given an intratumoral stereotaxic injection of murine fibroblasts
K. Culver +5 more
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Direct in situ introduction of exogenous genes into proliferating tumors could provide an effective therapeutic approach for treatment of localized tumors. Rats with a cerebral glioma were given an intratumoral stereotaxic injection of murine fibroblasts
K. Culver +5 more
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Examining horizontal gene transfer in microbial communities
Nature Reviews Microbiology, 2021I. Brito
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Gene Co-Inheritance and Gene Transfer
Science, 2007Functional transfer of mitochondrial genes to the nucleus is very common in some taxa but entirely lacking in others. Current evolutionary theories to account for this variation predict that outcrossing, which allows escape from Muller's ratchet and faster spread of beneficial mutations, should favor gene transfer. We find that functional gene transfer
Michael S. Barker +2 more
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2011
The endosymbiotic evolution of mitochondrial and plastid genomes from ancestral prokaryotes is outlined stressing the net passage of genes from the organelle precursor genomes to the nucleus. We highlight recent experimental analyses of the process of nucleic acid transfer between extant organelle genomes and the nucleus. The molecular events that have
Jeremy N. Timmis +4 more
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The endosymbiotic evolution of mitochondrial and plastid genomes from ancestral prokaryotes is outlined stressing the net passage of genes from the organelle precursor genomes to the nucleus. We highlight recent experimental analyses of the process of nucleic acid transfer between extant organelle genomes and the nucleus. The molecular events that have
Jeremy N. Timmis +4 more
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Novel Gene Transfer Systems: Intelligent Gene Transfer Vectors for Gene Medicines
Current Topics in Medicinal Chemistry, 2012Drug delivery systems for gene transfer are called 'vectors'. These systems were originally invented as a delivery system for the transfection in vitro or in vivo. Several vectors are then developed for clinical use of gene medicines and currently some of them are approved as animal drugs.
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1991
Gene transfer technology underpins both crop plant genetic engineering, where it is an obvious prerequisite, and the plant sciences generally, where it is becoming an essential tool for tackling fundamental problems in physiology, biochemistry, developmental biology, molecular biology and genetics.
R. Scott, J. Draper
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Gene transfer technology underpins both crop plant genetic engineering, where it is an obvious prerequisite, and the plant sciences generally, where it is becoming an essential tool for tackling fundamental problems in physiology, biochemistry, developmental biology, molecular biology and genetics.
R. Scott, J. Draper
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1985
Publisher Summary This chapter reviews data regarding the nature of evidence for gene transfer in fungi and the characterization of the transformants, and discuss the use of gene transfer as a genetic system to seek answers to several questions concerning the regulatory control and other basic mechanisms of eukaryotes. Fungi offer a unique system for
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Publisher Summary This chapter reviews data regarding the nature of evidence for gene transfer in fungi and the characterization of the transformants, and discuss the use of gene transfer as a genetic system to seek answers to several questions concerning the regulatory control and other basic mechanisms of eukaryotes. Fungi offer a unique system for
openaire +3 more sources