Results 91 to 100 of about 622,762 (337)
Gene Therapy for Pediatric Cancer: State of the Art and Future Perspectives [PDF]
, 2003 While modern treatments have led to a dramatic improvement in survival for pediatric malignancy, toxicities are high and a significant proportion of patients remain resistant.
Biagi, Ettore +3 more
core +5 more sources
Survivin and Aurora Kinase A control cell fate decisions during mitosis
Molecular Oncology, EarlyView.Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir +2 more
wiley +1 more source
The Intellectual and Technical Property Components of pro-Vitamin A Rice (GoldenRiceTM): A Preliminary Freedom-To-Operate Review [PDF]
, 2000 Rice is a staple food for millions of people, predominantly in Asia, but lacks essential nutritional components such as Vitamin A. This is very important for over 180 million children and women of child bearing age who suffer from Vitamin A deficiency in
Kowalski, Stanley P. +2 more
core +1 more source
Molecular Oncology, EarlyView.CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir +12 more
wiley +1 more source
New biotechnology enhances the application of cisgenesis in plant breeding
Frontiers in Plant Science, 2014 Cisgenesis is genetic modification to transfer beneficial alleles from crossable species into a recipient plant. The donor genes transferred by cisgenesis are the same as those used in traditional breeding.
Hongwei eHou +3 more
doaj +1 more source
Molecular bases and role of viruses in the human microbiome. [PDF]
, 2014 Viruses are dependent biological entities that interact with the genetic material of most cells on the planet, including the trillions within the human microbiome.
Abeles, Shira R, Pride, David T
core +1 more source
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
Molecular Therapy: Methods & Clinical Development, 2015 Recombinant adeno-associated virus (rAAV) is currently the best vector for gene delivery into the skeletal muscle. However, the 5-kb packaging size of this virus is a major obstacle for large gene transfer.
Marina Pryadkina +6 more
doaj +1 more source
Aquaculture Asia, Vol. 11, No. 2, pp.1-38. April-June 2006 [PDF]
, 2006 Selection of high-health postlarvae: a prerequisite for sustainability of the Indian shrimp industry, by S. Saurabh, V. Kumar, S. Karanth and G. Venkateshwarlu. Nucleotides: novel immunostimulants in aquaculture feed, by P. Kalaimani Arasi, N. Felix.
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Magnetic genes: Studying the genetics of biomineralization in magnetotactic bacteria. [PDF]
, 2020 Many species of bacteria can manufacture materials on a finer scale than those that are synthetically made. These products are often produced within intracellular compartments that bear many hallmarks of eukaryotic organelles.
KOMEILI, Arash, McCausland, Hayley
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