Results 1 to 10 of about 7,819,121 (415)

The thermodynamics of general anesthesia [PDF]

Biophys. J. 92 (2007) 3159-3165, 2006
It is known that the action of general anesthetics is proportional to their partition coefficient in lipid membranes (Meyer-Overton rule). This solubility is, however, directly related to the depression of the temperature of the melting transition found close to body temperature in biomembranes. We propose a thermodynamic extension of the Meyer-Overton
Heimburg, Thomas Rainer, Jackson, Andrew D.   +1 more
arxiv   +11 more sources

Spinal Anesthesia or General Anesthesia for Hip Surgery in Older Adults.

New England Journal of Medicine, 2021
BACKGROUND The effects of spinal anesthesia as compared with general anesthesia on the ability to walk in older adults undergoing surgery for hip fracture have not been well studied.
M. Neuman, Rui Feng, J. Carson, Lakisha J. Gaskins, D. Dillane, D. Sessler, F. Sieber, J. Magaziner, E. Marcantonio, S. Mehta, Diane A. Menio, S. Ayad, T. Stone, S. Papp, E. Schwenk, N. Elkassabany, Mitchell H. Marshall, J. D. Jaffe, Charles Luke, B. Sharma, Syed Azim, R. Hymes, K. Chin, R. Sheppard, B. Perlman, J. Sappenfield, E. Hauck, M. Hoeft, Mark Giska, Yatish S Ranganath, T. Tedore, Stephen Choi, Jinlei Li, M. K. Kwofie, A. Nader, R. Sanders, Brian F S Allen, K. Vlassakov, S. Kates, L. Fleisher, James Dattilo, A. Tierney, A. Stephens-Shields, S. Ellenberg   +43 more
semanticscholar   +1 more source

Quality of Recovery After General Anesthesia with Remimazolam in Patients’ Undergoing Urologic Surgery: A Randomized Controlled Trial Comparing Remimazolam with Propofol

Drug Design, Development and Therapy, 2022
Background Remimazolam is a new medication with sedative and hypnotic effects. It has been demonstrated non-inferior to propofol in general anesthesia with regard to efficacy and safety. However, whether general anesthesia with remimazolam is better than
Y. Mao, Jin-He Guo, Jingjing Yuan, Erxian Zhao, Jianjun Yang   +4 more
semanticscholar   +1 more source

Effect of Regional vs General Anesthesia on Incidence of Postoperative Delirium in Older Patients Undergoing Hip Fracture Surgery: The RAGA Randomized Trial.

Journal of the American Medical Association (JAMA), 2021
Importance In adults undergoing hip fracture surgery, regional anesthesia may reduce postoperative delirium, but there is uncertainty about its effectiveness.
Ting Li, Jun Li, Liyong Yuan, Jinze Wu, Chenchen Jiang, Jane Daniels, Rajnikant Mehta, Mingcang Wang, Joyce Yeung, Thomas Jackson, T. Melody, Shengwei Jin, Yinguang Yao, Jimin Wu, Junping Chen, F. G. Smith, Qingquan Lian   +16 more
semanticscholar   +1 more source

General Anesthesia versus Sedation, Both with Hemodynamic Control, during Intraarterial Treatment for Stroke: The GASS Randomized Trial

Anesthesiology, 2022
Background: It is speculated that the anesthetic strategy during endovascular therapy for stroke may have an impact on the outcome of the patients. The authors hypothesized that conscious sedation is associated with a better functional outcome 3 months ...
A. Maurice, F. Eugène, T. Ronzière, J. Devys, G. Taylor, A. Subileau, O. Huet, Hakim Gherbi, M. Laffon, M. Esvan, B. Laviolle, H. Beloeil   +11 more
semanticscholar   +1 more source

Efficacy of stylet angulation at the holding position during tracheal intubation with a videolaryngoscope: a randomized controlled trial

Scientific Reports, 2021
The aim of this randomized controlled trial was to determine the efficacy of stylet angulation at the holding position during tracheal intubation with a McGRATH MAC videolaryngoscope.
Ryo Wakabayashi, Yuki Shiko, Tomofumi Kodaira, Yuko Shiroshita, Hitomi Otsuka, Kosuke Baba, Norimasa Hishinuma   +6 more
doaj   +1 more source

Neuraxial and general anesthesia for outpatient total joint arthroplasty result in similarly low rates of major perioperative complications: a multicentered cohort study

Regional anesthesia and pain medicine, 2022
Background Neuraxial anesthesia when compared with general anesthesia has shown to improve outcomes following lower extremity total joint arthroplasty.
E. Yap, Julia C. Wei, Christopher Webb, K. Ng, M. Behrends   +4 more
semanticscholar   +1 more source

Pharmacodynamic modeling of moderate sedation and rationale for dosing using midazolam, propofol and alfentanil

BMC Pharmacology and Toxicology, 2023
Purpose Regulations have broadened to allow moderate sedation administration for gastrointestinal endoscopy by non-anesthesia personnel. The line between moderate and deep sedation is ambiguous.
Jing-Yang Liou, I-Ting Kuo, Weng-Kuei Chang, Chien-Kun Ting, Mei-Yung Tsou   +4 more
doaj   +1 more source

Randomized, controlled trial comparing respiratory and analgesic effects of interscalene, anterior suprascapular, and posterior suprascapular nerve blocks for arthroscopic shoulder surgery [PDF]

Korean Journal of Anesthesiology, 2020
Background Interscalene brachial plexus block (ISB) provides excellent analgesia for arthroscopic shoulder surgeries but is associated with adverse effects including hemidiaphragmatic paresis.
Yean Chin Lim, Zhao Kun Koo, Vivian. W. Ho, See Seong Chang, Shivani Manohara, Qian Jun Tong   +5 more
doaj   +1 more source

Development and prospective validation of postoperative pain prediction from preoperative EHR data using attention-based set embeddings

npj Digital Medicine, 2023
Preoperative knowledge of expected postoperative pain can help guide perioperative pain management and focus interventions on patients with the greatest risk of acute pain.
Ran Liu, Rodrigo Gutiérrez, Rory V. Mather, Tom A. D. Stone, Laura A. Santa Cruz Mercado, Kishore Bharadwaj, Jasmine Johnson, Proloy Das, Gustavo Balanza, Ekenedilichukwu Uwanaka, Justin Sydloski, Andrew Chen, Mackenzie Hagood, Edward A. Bittner, Patrick L. Purdon   +14 more
doaj   +1 more source