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The Thermodynamics of General Anesthesia [PDF]
It is known that the action of general anesthetics is proportional to their partition coefficient in lipid membranes (Meyer-Overton rule). This solubility is, however, directly related to the depression of the temperature of the melting transition found close to body temperature in biomembranes. We propose a thermodynamic extension of the Meyer-Overton
Heimburg, Thomas Rainer+1 more
openaire +4 more sources
The Current Role of General Anesthesia for Cesarean Delivery
The use of general anesthesia for cesarean delivery has declined in the last decades due to the widespread utilization of neuraxial techniques and the understanding that neuraxial anesthesia can be provided even in urgent circumstances. In fact, the role
Laurence E. Ring, R. Landau, C. Delgado
semanticscholar +1 more source
The pulmonary endothelium is an immediate recipient of high oxygen concentrations upon oxygen therapy and mediates down‐stream responses. Cyclic collapse and reopening of atelectatic lung areas during mechanical ventilation with high fractions of ...
Peter Wohlrab+8 more
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Background: Delirium is a common and serious postoperative complication, especially in the elderly. Epidural anesthesia may reduce delirium by improving analgesia, reducing opioid consumption, and blunting stress response to surgery. This trial therefore
Ya-wei Li+20 more
semanticscholar +1 more source
History of anesthesia usage in dentistry [PDF]
Since prehistoric times, man has sought ways to lessen pain. With varying degrees of success he has utilized: opium, nerve compresses, cold, hypnosis, etc.
Koković Vladimir
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General anesthesia vs. non-general anesthesia for vertebrobasilar stroke endovascular therapy
BackgroundThe optimal type of anesthesia for acute vertebrobasilar artery occlusion (VBAO) remains controversial. We aimed to assess the influence of anesthetic management on the outcomes in VBAO patients received endovascular treatment (EVT ...
Yanan Lu+14 more
doaj +1 more source
BACKGROUND Sedation with propofol injections is associated with a risk of addiction, but remimazolam benzenesulfonate is a comparable anesthetic with a short elimination half-life and independence from cell P450 enzyme metabolism. Compared to remimazolam,
Fang Tang+7 more
semanticscholar +1 more source
Background: Experimental and observational research suggests that combined epidural–general anesthesia may improve long-term survival after cancer surgery by reducing anesthetic and opioid consumption and by blunting surgery-related inflammation.
Yaoan Du+21 more
semanticscholar +1 more source
Prenatal Exposure to General Anesthesia and Childhood Behavioral Deficit
BACKGROUND: Exposure to surgery and anesthesia in early childhood has been found to be associated with an increased risk of behavioral deficits. While the US Food and Drug Administration (FDA) has warned against prenatal exposure to anesthetic drugs ...
C. Ing+6 more
semanticscholar +1 more source
Noninvasive respiratory support for COVID-19 patients: when, for whom, and how?
The significant mortality rate and prolonged ventilator days associated with invasive mechanical ventilation (IMV) in patients with severe COVID-19 have incited a debate surrounding the use of noninvasive respiratory support (NIRS) (i.e., HFNC, CPAP, NIV)
Zachary P. Sullivan+5 more
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