Results 11 to 20 of about 7,819,121 (415)

General anesthesia reduces complexity and temporal asymmetry of the informational structures derived from neural recordings in Drosophila [PDF]

open access: yesPhys. Rev. Research 2, 023219 (2020), 2019
We apply techniques from the field of computational mechanics to evaluate the statistical complexity of neural recording data from fruit flies. First, we connect statistical complexity to the flies' level of conscious arousal, which is manipulated by general anesthesia (isoflurane).
Cohen, Dror   +7 more
arxiv   +3 more sources

Stabilizing membrane domains antagonizes n-alcohol anesthesia [PDF]

open access: yesBiophysical Journal, Volume 111, Issue 3, 9 August 2016, Pages 537-545, 2016
Diverse molecules induce general anesthesia with potency strongly correlated both with their hydrophobicity and their effects on certain ion channels. We recently observed that several n-alcohol anesthetics inhibit heterogeneity in plasma membrane derived vesicles by lowering the critical temperature ($T_c$) for phase separation.
Brooks, NJ   +7 more
arxiv   +5 more sources

The Thermodynamics of General and Local Anesthesia [PDF]

open access: yesBiophysical Journal, 2014
General anesthetics are known to cause depression of the freezing point of transitions in biomembranes. This is a consequence of ideal mixing of the anesthetic drugs in the membrane fluid phase and exclusion from the solid phase. Such a generic law provides physical justification of the famous Meyer-Overton rule.
Graesboll, Kaare   +2 more
openaire   +7 more sources

General Anesthesia, Sleep, and Coma [PDF]

open access: yesNew England Journal of Medicine, 2010
This review discusses the clinical and neurophysiological features of general anesthesia and their relationships to sleep and coma, focusing on the neural mechanisms of unconsciousness induced by selected intravenous anesthetic drugs.
Schiff, Nicholas D.   +2 more
openaire   +6 more sources

The Neural Circuits Underlying General Anesthesia and Sleep.

open access: yesAnesthesia and Analgesia, 2021
General anesthesia is characterized by loss of consciousness, amnesia, analgesia, and immobility. Important molecular targets of general anesthetics have been identified, but the neural circuits underlying the discrete end points of general anesthesia ...
Olivia A. Moody   +6 more
semanticscholar   +1 more source

Delirium in Older Patients after Combined Epidural–General Anesthesia or General Anesthesia for Major Surgery: A Randomized Trial

open access: yesAnesthesiology, 2021
Background: Delirium is a common and serious postoperative complication, especially in the elderly. Epidural anesthesia may reduce delirium by improving analgesia, reducing opioid consumption, and blunting stress response to surgery. This trial therefore
Ya-wei Li   +20 more
semanticscholar   +1 more source

History of anesthesia usage in dentistry [PDF]

open access: yesStomatološki glasnik Srbije, 2005
Since prehistoric times, man has sought ways to lessen pain. With varying degrees of success he has utilized: opium, nerve compresses, cold, hypnosis, etc.
Koković Vladimir
doaj   +1 more source

The Current Role of General Anesthesia for Cesarean Delivery

open access: yesCurrent Anesthesiology Reports, 2021
The use of general anesthesia for cesarean delivery has declined in the last decades due to the widespread utilization of neuraxial techniques and the understanding that neuraxial anesthesia can be provided even in urgent circumstances. In fact, the role
Laurence E. Ring, R. Landau, C. Delgado
semanticscholar   +1 more source

Oxygen conditions oscillating between hypoxia and hyperoxia induce different effects in the pulmonary endothelium compared to constant oxygen conditions

open access: yesPhysiological Reports, 2021
The pulmonary endothelium is an immediate recipient of high oxygen concentrations upon oxygen therapy and mediates down‐stream responses. Cyclic collapse and reopening of atelectatic lung areas during mechanical ventilation with high fractions of ...
Peter Wohlrab   +8 more
doaj   +1 more source

General anesthesia vs. non-general anesthesia for vertebrobasilar stroke endovascular therapy

open access: yesFrontiers in Neurology, 2023
BackgroundThe optimal type of anesthesia for acute vertebrobasilar artery occlusion (VBAO) remains controversial. We aimed to assess the influence of anesthetic management on the outcomes in VBAO patients received endovascular treatment (EVT ...
Yanan Lu   +14 more
doaj   +1 more source

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