Obesity in children and general anesthesia
GSC Biological and Pharmaceutical Sciences, 2022 Childhood obesity has reached epidemic levels in developed as well as in developing countries. Overweight and obesity in childhood are known to have significant impact on both physical and psychological health. Obese 10-year-old boy undergoes general anesthesia for emergency peritonitis surgery. The purpose of this study was to study the intraoperative
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Cardiovascular changes after administration of aerosolized salbutamol in horses: five cases [PDF]
, 2014 Prevention and treatment of intraoperative hypoxemia in horses is difficult and both efficacy and safety of therapeutic maneuvers have to be taken into account.
AE Wagner +24 more
core +4 more sources
Membrane Nanodomains Homeostasis During Propofol Anesthesia as Function of Dosage and Temperature [PDF]
, 2020 Some anesthetics bind and potentiate gamma-aminobutyric-acid-type receptors, but no universal mechanism for general anesthesia is known. Furthermore, often encountered complications such as anesthesia induced amnesia are not understood. General anesthetics are hydrophobic molecules easily dissolving into lipid bilayers.
arxiv +1 more source
PLoS ONE, 2020 Exposure to general anesthesia has been reported to induce neurotoxicity, impair learning, memory, attention, motor functions, as well as affect behavior in adult rodents and nonhuman primates.
Yu-Pin Feng +4 more
semanticscholar +1 more source
Protocol for the Reconstructing Consciousness and Cognition (ReCCognition) Study [PDF]
, 2017 Important scientific and clinical questions persist about general anesthesia despite the ubiquitous clinical use of anesthetic drugs in humans since their discovery.
Andrew R. McKinstry-Wu +10 more
core +3 more sources
The anesthetic sevoflurane induces tau trafficking from neurons to microglia
Communications Biology, 2021 Using their previously developed nanobeam-sensor technology to detect tau protein in the blood, Yuanlin Dong et al. find that the anaesthetic sevoflurane induces trafficking of tau from neurons to microglia in mice.
Yuanlin Dong +8 more
doaj +1 more source
A Model-Based Architecture for Automatic Anesthesia Infusion [PDF]
arXiv, 2021 This paper presents a model-based control architecture. Based on the Medical Cyber-physical Systems (MCPS) concept, we construct a safe and reliable automatic anesthesia control closed-loop system. The control architecture uses the patient's propofol pharmacokinetic/pharmacodynamic model, using the calculated results as a feedback signal to correct the
arxiv
Hybrid Deep Neural Network for Brachial Plexus Nerve Segmentation in Ultrasound Images [PDF]
, 2021 Ultrasound-guided regional anesthesia (UGRA) can replace general anesthesia (GA), improving pain control and recovery time. This method can be applied on the brachial plexus (BP) after clavicular surgeries. However, identification of the BP from ultrasound (US) images is difficult, even for trained professionals.
arxiv +1 more source
Improved costs and outcomes with conscious sedation vs general anesthesia in TAVR patients: Time to wake up? [PDF]
, 2017 BackgroundTranscatheter aortic valve replacement (TAVR) has become a commonplace procedure for the treatment of aortic stenosis in higher risk surgical patients.
Aksoy, Olcay +10 more
core +3 more sources
Real-time Projected Gradient-based Nonlinear Model Predictive Control with an Application to Anesthesia Control [PDF]
, 2022 Medical drug infusion problems pose a combination of challenges such as nonlinearities from physiological models, model uncertainty due to inter- and intra-patient variability, as well as strict safety specifications. With these challenges in mind, we propose a novel real-time Nonlinear Model Predictive Control (NMPC) scheme based on projected gradient
arxiv +1 more source