Results 181 to 190 of about 77,183 (300)

Risk of Retinopathy Associated with Long‐Term Use of Hydroxychloroquine in Patients with Rheumatic Diseases: A Systematic Review and Meta‐Analysis

Arthritis Care &Research, Accepted Article.
Objective We aimed to estimate the prevalence and cumulative incidence of hydroxychloroquine retinopathy (HCQ‐R) and its risk factors among long‐term HCQ users with rheumatic diseases through a systematic review and meta‐analysis of observational studies that used spectral‐domain OCT (SD‐OCT) for screening. Methods A systematic search of PubMed, Scopus,
Narsis Daftarian, Chloe Yue, Steve D Levasseur, Hui Xie, J. Antonio Avina‐Zubieta   +4 more
wiley   +1 more source

The effect of general anesthetics on neutrophil-like differentiated HL60 cells: sevoflurane activates the mitochondrial function to promote their bactericidal action. [PDF]

Biochem Biophys Rep
Asei K, Nomura Y, Fujimoto D, Ooi M, Obata N, Mizobuchi S.   +5 more
europepmc   +1 more source

Clinical Significance of Therapeutic Drug Level Monitoring for Mycophenolate in Patients with Extra‐Renal Systemic Lupus Erythematosus – A Systematic Review & Meta‐analysis

Arthritis Care &Research, Accepted Article.
Background Clinical response to Mycophenolic acid (MPA) is highly heterogeneous; thus, therapeutic drug monitoring (TDM) may help improve treatment efficacy. This systematic review and meta‐analysis examined therapeutic ranges for MPA levels associated with better outcomes and safety in patients with SLE, particularly those with extra‐renal ...
Zahraa Qamhieh, Dalia Sriwi, Callie Saric, Tripti Singh, Christie M. Bartels, Shivani Garg   +5 more
wiley   +1 more source

Novel Spiro-Barbiturates Can Reverse the Action of General Anesthetics on the GABA_AR. [PDF]

J Med Chem
Koinas D, Zhou X, Wu B, Miller KW, Bruzik KS.   +4 more
europepmc   +1 more source

General Anesthetics on Immune System Cytokines: A Narrative Review Article. [PDF]

Anesth Pain Med, 2020
Jafarzadeh A, Hadavi M, Hassanshahi G, Rezaeian M, Vazirinejad R.   +4 more
europepmc   +1 more source

Developing and Evaluating a Laboratory‐Based Frailty Index (FI‐Lab) for the Prediction of Long‐Term Health Outcomes in Systemic Lupus Erythematosus

Arthritis Care &Research, Accepted Article.
Objective We aimed to construct and evaluate the first laboratory‐based frailty index (FI‐Lab) for predicting adverse outcomes in systemic lupus erythematosus (SLE) and to compare its predictive ability to that of an existing clinical frailty index (FI).
Grace Burns, Samuel D. Searle, Alexandra Legge   +2 more
wiley   +1 more source

Cannabinoids and General Anesthetics: Revisiting Molecular Mechanisms of Their Pharmacological Interactions. [PDF]

Anesth Analg
Echeverria-Villalobos M, Fabian CA, Mitchell JG, Mazzotta E, Fiorda Diaz JC, Noon K, Weaver TE.   +6 more
europepmc   +1 more source

High Healthcare Utilization Preceding Diagnosis with Juvenile Idiopathic Arthritis

Arthritis Care &Research, Accepted Article.
Objective Though early diagnosis improves long‐term outcomes, Juvenile Idiopathic Arthritis (JIA) patients often experience prolonged, circuitous paths to diagnosis. To inform diagnostic improvement, we sought to characterize healthcare utilization in the year preceding diagnosis.
Anna Costello, Rui Xiao, Xuemei Zhang, Jahan Jazayeri, Irit R Rasooly, Pamela F Weiss   +5 more
wiley   +1 more source

In vivo assessment of the influence of general anesthetics on transmembrane water cycling in the brain. [PDF]

J Cereb Blood Flow Metab
Cavallari E, Lorenzi E, Di Gregorio E, Ferrauto G, Aime S, Vallortigara G, Bifone A.   +6 more
europepmc   +1 more source

General anesthetics activate a potent central pain-suppression circuit in the amygdala. [PDF]

Nat Neurosci, 2020
Hua T, Chen B, Lu D, Sakurai K, Zhao S, Han BX, Kim J, Yin L, Chen Y, Lu J, Wang F.   +10 more
europepmc   +1 more source