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This study develops 3D‐printed Mg‐MC/PLGA scaffolds with varying Mg concentrations (0–20%). The 5% Mg scaffold shows optimal cytocompatibility, osteogenic activity in vitro, and significantly enhances bone regeneration in rabbits, improving bone volume and mechanical strength.
Shihang Liu +9 more
wiley +1 more source
Charge‐opposed reduced graphene oxide fillers are co‐integrated into biopolymeric nanocomposite scaffolds, synergistically enhance osteogenesis. Multiscale characterization reveals how surface chemistry and porosity dictate ectopic mineral architecture.
George Mihail Vlăsceanu +8 more
wiley +1 more source
Good Practice in Postoperative and Procedural Pain Management 2nd Edition [PDF]
CARTER, BERNIE +10 more
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This work presents a “tooth‐on‐chip” device that mimics dental pulp tissue. By co‐culturing key cell types, it recreates vascular networks, stem cell niches, the odontoblast/dentine interface, and trigeminal innervation. This innovative platform provides a unique model of dental pulp structure and physiology, with significant potential for accelerating
Alessandro Cordiale +6 more
wiley +1 more source
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International Anesthesiology Clinics, 1994
General anesthesia is the most common form of anesthetic management for ambulatory surgery. Patients, in general, prefer general anesthesia because it is less anxiety provoking. During the last decade, the availability of several short-acting agents with high clearance has made general anesthetic techniques much safer and more predictable for ...
Carmen R. Green, Sujit K. Pandit
openaire +3 more sources
General anesthesia is the most common form of anesthetic management for ambulatory surgery. Patients, in general, prefer general anesthesia because it is less anxiety provoking. During the last decade, the availability of several short-acting agents with high clearance has made general anesthetic techniques much safer and more predictable for ...
Carmen R. Green, Sujit K. Pandit
openaire +3 more sources
Evaluation of a General Anesthetic
JAMA, 1981Isoflurane is a nonflammable halogenated ether used as an inhalational anesthetic. It has physical, pharmacologic, and clinical properties similar to those of halothane and enflurane; however, it differs in important respects from both. It is a more potent muscle relaxant than halothane and does not have the CNS irritant properties of enflurane.
Michael H. M. Dykes, Harry W. Linde
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2006
Publisher Summary In surgical practice, the term general anesthesia (narcosis) presently refers to the condition of an organism with a reversible loss of consciousness at a controlled level of nervous system suppression. It includes components such as analgesia (absence of pain), amnesia (absence of memory), and suppression of reflexes such as ...
Victor J. Hruby, Ruben Vardanyan
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Publisher Summary In surgical practice, the term general anesthesia (narcosis) presently refers to the condition of an organism with a reversible loss of consciousness at a controlled level of nervous system suppression. It includes components such as analgesia (absence of pain), amnesia (absence of memory), and suppression of reflexes such as ...
Victor J. Hruby, Ruben Vardanyan
openaire +3 more sources
Anaphylaxis to General Anesthetics
2010The incidence of hypersensitivity reactions to anesthetics is estimated 1 in 13,000 anesthetics up to 1 in 3,180. The rate of mortality ranges between 3 and 9%. 90% of reactions appear at anesthesia induction. Cardiovascular collapse and bronchospasm are more frequent in IgE-dependent reactions.
D. Anne Moneret-Vautrin +1 more
openaire +2 more sources
Antagonism of general anesthetics
International Congress Series, 2005Abstract Despite many research efforts on the mechanisms of anesthesia, there have been no reports on the anesthesia antagonists. It is well recognized that the dose–response curves of anesthetics are extremely steep. Availability of anesthesia antagonists would benefit anesthesia practice at emergency situations when the anesthesia becomes ...
Ikuo Ueda, Tsuneo Tatara, Hiroshi Kamaya
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Neurotoxicity of General Anesthetics: An Update
Current Pharmaceutical Design, 2012Though general anesthetics have now been used clinically for well over a century, both their mechanisms of action as well as the nature of any potentially neurotoxic side effects remain elusive. With roughly 234 million people undergoing surgery each year worldwide, it remains imperative that any potentially deleterious effects of anesthetics be ...
Zhongcong Xie, Phillip E. Vlisides
openaire +3 more sources

