Results 91 to 100 of about 14,678,873 (255)

Combining ability studies for yield and yield components trait in hybrid rice (Oryza sativa L.) [PDF]

open access: yesElectronic Journal of Plant Breeding, 2012
Fifty two hybrids were generated from crossing four CMS lines and thirteen restorer lines in line x tester design. Crosses along with parents were evaluated for yield and yield component traits during rabi, 2011 at RARS, Jagtial, Andhra Pradesh ...
P.V. Padmavathi, P.V. Satyanarayana , Lal Ahamed M.,Y. Ashoka Rani and V. Srinivasa Rao
doaj  

The utility of covariance of combining ability in plant breeding

open access: yes, 1976
The definition of covariances of half- and full sibs, and hence that of variances of general and specific combining ability with regard to a quantitative character, is extended to take into account the respective covariances between a pair of characters.
Arunachalam , V.
core   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

open access: yesFEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Combining ability analysis for seed yield and component traits in Indian mustard [Brassica juncea (L.) Czern & Coss.] [PDF]

open access: yesElectronic Journal of Plant Breeding, 2015
Combining ability of eight quantitative traits was studied in 12 lines, 4 testers and 48 F1’s in Line x Tester mating design to know the inheritance pattern of yield attributes of Indian mustard [Brassica juncea (L.) Czern & Coss].
Gideon J. Synrem*, N. R. Rangare, Anil K. Choudhari, Sujeet Kumar and Ibadaiahun Myrthong
doaj  

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Improving forecast accuracy by combining recursive and rolling forecasts [PDF]

open access: yes
This paper presents analytical, Monte Carlo, and empirical evidence on the effectiveness of combining recursive and rolling forecasts when linear predictive models are subject to structural change. We first provide a characterization of the bias-variance
Todd E. Clark, Michael W. McCracken
core  

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

Combining ability for yield and yield-associated traits in wheat (Triticum aestivum L.)

open access: yesElectronic Journal of Plant Breeding
The current breeding effort aims to develop new wheat genotypes with higher genetic potential, thereby contributing to food security. Ten wheat genotypes were crossed in a half-diallel mating design.
Afsar Ahmad1 and Rajesh Kumar Gupta2
doaj   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

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