Results 101 to 110 of about 431,391 (303)

COMBINING ABILITY OF SWEET PEPPER BREEDING LINES FOR THE MAIN COMPONENTS OF YIELD

open access: yes, 2017
The important stage of breeding program for F1 hybrids with high yield capacity is to estimate the combining ability of parental lines for productivity characteristics.
O. N. Shlijomka   +3 more
core   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Effects of the combining ability on mirador chili (Capsicum annuum L.) populations native to Veracruz, Mexico

open access: yes, 2023
Objective: Evaluate the effects of general and specific combining ability in agronomic characters of native populations of mirador pepper and identify genotypes with potential for the genetic improvement of the crop.
Chávez-Aguilar, Griselda   +4 more
core   +1 more source

Studies on Combining Ability for Yield and Quality Traits in Brinjal (Solanum melongena L.)

open access: yesJournal of Horticultural Sciences, 2012
The experimental material in brinjal (eggplant) comprised 19 parents (15 lines + 4 testers), 60 F1 crosses and two standard checks (BH-1 and BH-2). This was grown in Randomized Block Design, with three replications. Lines vs.
Bharat Bhushan   +3 more
doaj   +1 more source

Association mapping for general combining ability with yield, plant height and ear height using F1 population in maize. [PDF]

open access: yesPLoS One, 2021
Zheng Y   +8 more
europepmc   +1 more source

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

open access: yesMolecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski   +12 more
wiley   +1 more source

General and Specific Combining Ability for Nine Morphologic Characters in Round Brinjal (Solanum melongena L.)

open access: yes, 2017
A study was undertaken to estimate general and specific combining in brinjal through diallel analysis involving 6 parents. The combining ability analysis revealed highly significant differences among the treatments for all the parameters studied except ...
Amit Kumar   +5 more
core   +1 more source

Combining ability studies for yield and yield components trait in hybrid rice (Oryza sativa L.) [PDF]

open access: yesElectronic Journal of Plant Breeding, 2012
Fifty two hybrids were generated from crossing four CMS lines and thirteen restorer lines in line x tester design. Crosses along with parents were evaluated for yield and yield component traits during rabi, 2011 at RARS, Jagtial, Andhra Pradesh ...
P.V. Padmavathi, P.V. Satyanarayana , Lal Ahamed M.,Y. Ashoka Rani and V. Srinivasa Rao
doaj  

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

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