Results 101 to 110 of about 14,678,873 (255)

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

Heterosis and combining ability for yield attributes and quality traits in tomato (Solanum lycopersicum) under mid hill conditions of Himachal Pradesh

open access: yesThe Indian Journal of Agricultural Sciences
The present investigation was undertaken to evaluate heterosis and combining ability among nine elite tomato (Solanum lycopersicum L.) genotypes and their 36 F₁ hybrids developed through a diallel mating design excluding reciprocals under mid-hill ...
BHUPINDER SINGH THAKUR   +4 more
doaj   +1 more source

Combining ability analysis for yield and yield components in bold grained rice (Oryza sativa L.) of Assam [PDF]

open access: yes, 2009
Combining ability analysis for grain yield and its components was carried out in eight parental diallel crosses of bold grained rice excluding reciprocals.
R Chakraborty   +7 more
core  

Genetic parameters of heritability and combining ability.

open access: yes, 2014
VG: variance of general combining ability (GCA); VS: variance of specific combining ability (SCA); Vgf: contribution ratio of the female GCA variance to the total variance; Vgm: contribution ratio of the male GCA variance to the total variance; Vgfm ...
Yongming Zhou (429711)   +2 more
core   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

open access: yesMolecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Heterosis and combining ability for yield and other agronomic traits in Triticale

open access: yesOpen Agriculture, 2018
The estimation of genetic parameters such as heterosis (Mh), heterobeltiosis (Hh), general combining ability (GCA) and specific combining ability (SCA) allows inferences about the predominant action of the genes, indicates the appropriate selection ...
Ferrari Enzo   +3 more
doaj   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

General combining ability (GCA) effects of parents (lines and testers) for the five measured traits.

open access: yes
General combining ability (GCA) effects of parents (lines and testers) for the five measured traits.
Yizhong Zhang (6034004)   +9 more
core   +1 more source

Combining ability studies in tropical sorghum (Sorghum bicolor (L.) Moench) [PDF]

open access: yes, 2004
Sorghum varieties grown in West Africa usually have low production potential. Information on combining ability of diverse open-pollinated cultivars and gene pools is needed for efficient choice of breeding methods and parental materials to use in ...
Alabi, S O, Kenga, R, Gupta, S C
core  

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