Results 121 to 130 of about 14,678,873 (255)

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

Evaluation of combining ability and genetic analysis for salinity tolerance in a 7 × 7 F1 half-diallel population of groundnut (Arachis hypogaea L.)

Discover Plants
A study was conducted at the net house of Sher-e-Bangla Agricultural University in Dhaka to develop salt-tolerant and high-yielding groundnut genotypes.
Md. Akram Hossain Chowdhury, Md. Shahidur Rashid Bhuiyan, Md. Shah-E-Alam, Md. Sarowar Hossain, Md. Fazlul Karim, Shahanaz Parveen, Md. Harun-Ur-Rashid   +6 more
doaj   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

Evaluating Maize Hybrids for Yield, Stress Tolerance, and Carotenoid Content: Insights into Breeding for Climate Resilience

Plants
To ensure food and feed security, modern maize hybrids must not only perform well under changing climate conditions but also consistently achieve higher and stable yields, exhibit maximum tolerance to stress factors, and produce high quality grains. In a
Călin Popa, Roxana Elena Călugăr, Andrei Varga, Edward Muntean, Ioan Băcilă, Carmen Daniela Vana, Ionuț Racz, Nicolae Tritean, Ioana Virginia Berindean, Andreea D. Ona, Leon Muntean   +10 more
doaj   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

Assessment of combining ability for grain yield and its attributing traits in maize (Zea mays L.)

Discover Agriculture
A comprehensive understanding of combining ability is an emerging focus in hybrid maize research in Nepal. The present study aimed to evaluate the performance of single-cross maize hybrids and to estimate the combining abilities of parental lines for ...
Jiban Shrestha, Surya Kant Ghimire, Krishna Hari Dhakal, Mahendra Prasad Tripathi   +3 more
doaj   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription

FEBS Open Bio, EarlyView.
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang, Mingqiang Deng, Dongmei He, Diqin Lai, Dongjun Liu, Dengyong Zhu, Zhenhua Zhang, Peng Tang, Chuanman Zhou, Menghui Yin, Xichen Bao   +10 more
wiley   +1 more source

Comprehensive study on combining ability, heritability and genetic advance for important morphological and biochemical traits in bread wheat (Triticumaestivum L.)

Discover Agriculture
In this study, 15 genetically diverse wheat genotypes (10 lines and 5 testers) and their 50 F₁ hybrids were evaluated using a randomized design for 13 morphological and 2 biochemical traits under normal environmental conditions.
Anand Kumar, Laxmidas Verma, Sagar, Prashant Kaushik, Prabhat Kumar, D. S. Mishra, Vikas Yadav, Prakashbhai Ravat, Prakash Yadav, Aina Yadav   +9 more
doaj   +1 more source

Exploring the influence of lactoferrin on wound healing and related signaling pathways: a systematic review

FEBS Open Bio, EarlyView.
Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo, Kátia Cristiane Hall, Matheus dos Santos Fernandez, Geovanna Peter Corrêa, Rafael Guerra Lund   +4 more
wiley   +1 more source