Results 61 to 70 of about 14,678,873 (255)
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Correlation between the performance of hybrids and combining ability.
, 2015 *, ** significant at p < 0.05, 0.001 respectively.See Table 2 for trait abbreviations.FGCA: female general combining ability; MGCA: male general combining ability; TGCA: total general combining ability, TGCA = FGCA+MGCA; SCA: special combining ability.MP:
Chao Lv (335727) +4 more
core +1 more source
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
General combining ability for agronomic and yield characters.
, 2015 *, ** significant at p < 0.05, 0.001 respectively.See Table 2 for trait abbreviationsGeneral combining ability for agronomic and yield characters.
Chao Lv (335727) +4 more
core +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Forecasting Organic Food Prices: Testing and Evaluating Conditional Predictive Ability [PDF]
Organic farmers, wholesalers, and retailers need reliable price forecasts to improve their decision- making practices. This paper presents a methodology and protocol to select the best-performing method from several time and frequency domain candidates ...
Lohr, Luanne +3 more
core
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Diallel Analysis of Early Leaf Spot (Cercospora arachidicola Hori) Disease Resistance in Groundnut
Agronomy, 2019 Early leaf spot (ELS) is one of the major biotic constraints of groundnut production in West and Central Africa. A study using 6 × 6 F2 full diallel populations from six parents (NAMA, B188, PC79-79, QH243C, TS32-1, and CN94C) was conducted to ...
Adama Zongo +6 more
doaj +1 more source