Results 51 to 60 of about 263,496 (313)

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

General decay stability of stochastic functional differential equations [PDF]

open access: yes, 2014
In this thesis, pth moment and almost sure stability on a general decay rate for several types of stochastic functional differential equations were studied. By applying Razumikhin method and Lyapunov method stability criteria were obtained.
Pavlović-Rajković, Gorica A.
core   +1 more source

Stability of neutral pantograph stochastic differential equations with generalized decay rate

open access: yesSystems Science & Control Engineering, 2022
In this paper, we investigate the stability of highly nonlinear hybrid neutral pantograph stochastic differential equations (NPSDEs) with general decay rate.
Mingxuan Shen, Xue Gong, Yingjuan Yang
doaj   +1 more source

Off-Shell Effects for Single Top-Quark Production Processes at Hadron Colliders [PDF]

open access: yes, 2011
We present a calculation of s- and t-channel single top-quark production and decay at next-to-leading order in QCD for the Tevatron and for the LHC. The calculation includes the off-shell effects of the intermediate top-quark and the non-factorisable ...
MELLOR, PAUL
core  

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

open access: yesFEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro   +1 more
wiley   +1 more source

Generalized effective operator formalism for decaying systems [PDF]

open access: yesPhysical Review A, 2016
11 pages, 20 ...
Paraschiv, Marius   +3 more
openaire   +2 more sources

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

open access: yesFEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya   +2 more
wiley   +1 more source

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi   +2 more
wiley   +1 more source

Probing supersymmetry with third-generation cascade decays [PDF]

open access: yesJournal of High Energy Physics, 2009
The chiral structure of supersymmetric particle couplings involving third generation Standard Model fermions depends on left-right squark and slepton mixings as well as gaugino-higgsino mixings. The shapes and intercorrelations of invariant mass distributions of a first or second generation lepton with bottoms and taus arising from adjacent branches of
Graesser, Michael, Shelton, Jessie
openaire   +2 more sources

Clustering Algorithm Reveals Dopamine‐Motor Mismatch in Cognitively Preserved Parkinson's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore the relationship between dopaminergic denervation and motor impairment in two de novo Parkinson's disease (PD) cohorts. Methods n = 249 PD patients from Parkinson's Progression Markers Initiative (PPMI) and n = 84 from an external clinical cohort.
Rachele Malito   +14 more
wiley   +1 more source

Home - About - Disclaimer - Privacy