Results 61 to 70 of about 1,246,943 (339)

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Time decay of scaling invariant Schroedinger equations on the plane [PDF]

, 2014
We prove the sharp L^1-L^{\infty} time-decay estimate for the 2D-Schroedinger equation with a general family of scaling critical electromagnetic potentials.Comment: 26 ...
Fanelli, L., Felli, V., Fontelos, M., Primo, A.   +3 more
core   +1 more source

The Formalism of Generalized Contexts and Decay Processes

International Journal of Theoretical Physics, 2012
The formalism of generalized contexts for quantum histories is used to investigate the possibility to consider the survival probability as the probability of no decay property at a given time conditional to no decay property at an earlier time. A negative result is found for an isolated system.
Losada, Marcelo Adrián, Laura, Roberto Domingo Eugenio   +1 more
openaire   +3 more sources

Prompt decays of general neutralino NLSPs at the Tevatron [PDF]

Journal of High Energy Physics, 2010
Recent theoretical developments have shown that gauge mediation has a much larger parameter space of possible spectra and mixings than previously considered. Motivated by this, we explore the collider phenomenology of gauge mediation models where a general neutralino is the lightest MSSM superpartner (the NLSP), focusing on the potential reach from ...
Meade, Patrick, Reece, Matthew, Shih, David   +2 more
openaire   +5 more sources

Characterization of WAC interactions with R2TP and TTT chaperone complexes linking glucose and glutamine availability to mTORC1 activity

FEBS Open Bio, EarlyView.
TTT and R2TP chaperone complexes are required for the assembly and activation of mTORC1. WAC directly interacts with components of TTT, R2TP, and mTORC1, and these interactions are affected by the availability of glucose and glutamine, correlating with changes in mTORC1 activity.
Sofía Cabezudo, Natalia Cuervo, Carmen García‐Martín, Andrés López‐Perrote, Clara Reglero, Adrián Maqueda‐Real, Ana González‐Corpas, Marina Serna, Diego Megías, Alejo Efeyan, Solip Park, Oscar Llorca   +11 more
wiley   +1 more source

How large could the R-parity violating couplings be?

, 2004
We investigate in detail the predictions coming from the d=4 operators for proton decay. We find the most general constraints for the R-parity violating couplings coming from proton decay, taking into account all fermion mixing and in different ...
Allanach B (R-parity Working Group Collaboration), Anchordoqui L Goldberg H Nunez C, Antoniadis I Dimopoulos S, Arkani-Hamed N Dimopoulos S, Arkani-Hamed N Dimopoulos S Giudice G F Romanino A, Arvanitaki A Davis C Graham P W Wacker J G, Aulakh C S Girdhar A, Aurelio Diaz M Fileviez Pérez P, Bajc B Fileviez Pérez P Senjanović G, Bajc B Senjanovic G, Barbier R, Binger M, Cheung K Keung W Y, Chun E J Park S C, Dorsner I Fileviez Pérez P, Dreiner H K, Georgi H, Hewett J L, Jung C K, Kokorelis C, Kors B Nath P, Mahbubani R, Masiero A Profumo S Ullio P, Mukhopadhyaya B SenGupta S, Pavel Fileviez Pérez, Rubbia A   +25 more
core   +1 more source

The impact of Hnrnpl deficiency on transcriptional patterns of developing muscle cells

FEBS Open Bio, EarlyView.
We performed nanopore whole‐transcriptome sequencing comparing RNA from Hnrnpl‐knockdown versus control C2C12 myoblasts to investigate the contributions of Hnrnpl to muscle development. Our results indicate that Hnrnpl regulates the expression of genes involved with Notch signaling and skeletal muscle, particularly splicing patterns of specific muscle ...
Hannah R. Littel, Mekala Gunasekaran, Audrey L. Daugherty, Natalya M. Wells, Johnnie Turner, Christine C. Bruels, Christina A. Pacak, Isabelle Draper, Peter B. Kang   +8 more
wiley   +1 more source

Fermionic decay of a massive scalar in the early Universe

, 2019
We derive a curved space generalization of a scalar to fermion decay rate with a Yukawa coupling in expanding Friedmann-Robertson-Walker universes. This is done using the full theory of quantum fields in curved spacetime and the added-up transition ...
Lankinen, Juho, Malmi, Joonas, Vilja, Iiro   +2 more
core   +1 more source

Effect of dissipation on the decay-rate phase transition [PDF]

, 1998
A general condition for sharp transition of decay rate from quantum to thermal regimes is derived in dissipative tunneling models when position dependent mass is involved.
Kim, Hungsoo, Kim, Jae Kwan, lee, Soo-Young, Park, Chang Soo, Park, D. K.   +4 more
core   +2 more sources

Probing supersymmetry with third-generation cascade decays [PDF]

Journal of High Energy Physics, 2009
The chiral structure of supersymmetric particle couplings involving third generation Standard Model fermions depends on left-right squark and slepton mixings as well as gaugino-higgsino mixings. The shapes and intercorrelations of invariant mass distributions of a first or second generation lepton with bottoms and taus arising from adjacent branches of
Michael L. Graesser, Jessie Shelton
openaire   +3 more sources