Results 111 to 120 of about 7,354,336 (371)

Adenosine A3 receptor antagonists as anti‐tumor treatment in human prostate cancer: an in vitro study

open access: yesFEBS Open Bio, EarlyView.
The A3 adenosine receptors (A3ARs) are overexpressed in prostate cancer. AR 292 and AR 357, as A3AR antagonists, are capable of blocking proliferation, modulating the expression of drug transporter genes involved in chemoresistance, ferroptosis, and the hypoxia response, and inducing cell death.
Maria Beatrice Morelli   +15 more
wiley   +1 more source

MODEL METHODS OF UPBRINGING OF PUPILS IN THE LEARNING PROCESS OF BIOLOGY AND ECOLOGY

open access: yesВестник Северо-Кавказского федерального университета, 2022
One of the priorities of school education is the upbringing ofpupils. Educational subject's biology and ecology solve this problem by their own means. The problem of upbringing of pupils faced the methodology of teaching biology and ecology at all times.
A. Semenov
doaj  

Developing a custom GPT based on Inquiry Based Learning for Physics Teachers [PDF]

open access: yesarXiv
Generative Artificial Intelligence (GenAI) has emerged as a valuable assistant in many fields such as marketing, finance, project management, and education. In education, many GenAI tools have been developed to aid teachers in preparing proper educational material and offering personalized learning to their students, tailored to their educational needs.
arxiv  

AS-938-22 Resolution on AB 928 and Common GE Pathway [PDF]

open access: yes, 2022
Urges the Office of the Chancellor to satisfy AB 928 compliance requirements via a 12-course IGETC pathway or, alternatively, via coded memorandum that exempts prospective transfer students from taking all 12 IGETC lower-division courses and, instead ...
General Education Governance Board,
core   +1 more source

Downregulation of O‐GlcNAcylation enhances etoposide‐induced p53‐mediated apoptosis in HepG2 human liver cancer cells

open access: yesFEBS Open Bio, EarlyView.
Etoposide, a topoisomerase II inhibitor, reduces O‐GlcNAcylation in HepG2 liver cancer cells. Further inhibition of O‐GlcNAc transferase by OSMI‐1 enhanced etoposide‐induced apoptosis, lowering the IC50 for viability and increasing the EC50 for cytotoxicity.
Jaehoon Lee   +5 more
wiley   +1 more source

Co‐expression of HSV‐1 ICP34.5 enhances the expression of gene delivered by self‐amplifying RNA and mitigates its immunogenicity

open access: yesFEBS Open Bio, EarlyView.
ICP34.5 is one of the most important antihost response proteins. The saRNA‐encoding HSV‐1 neurovirulence protein ICP34.5 clearly mediated the eukaryotic initiation factor 2 alpha subunit (eIF2α) dephosphorylation and significant suppression of innate immune responses in vitro, leading to enhanced expression of the saRNA‐encoded gene.
Xuemin Lu   +6 more
wiley   +1 more source

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