Results 121 to 130 of about 7,269,794 (356)

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

Validity and reliability of the questionnaire of academic knowledge of teachers of basic general education. [PDF]

open access: yesF1000Res, 2023
Basantes-Andrade A   +3 more
europepmc   +1 more source

Education, Gender and Earnings in France and Germany: Level and Dispersion Effects [PDF]

open access: yes
This paper analyses the relationship between education, gender and earnings in France and Germany. The model chosen here enables to estimate the impact of education not only on the expected earnings level but also on their dispersion, taking gender ...
Lauer, Charlotte
core  

City College, Manchester (FEFC inspection report; 62/96 and 82/00) [PDF]

open access: yes, 2000
Comprises two Further Education Funding Council (FEFC) inspection reports for the periods 1995-96 (62/96), and 1999-2000 (82/00). The FEFC has a legal duty to make sure further education in England is properly assessed.

core  

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

The Armed Forces Covenant in action?: Part 4: Education of service personnel fifth report of session 2013-14 report, together with formal minutes, oral and written evidence [PDF]

open access: yes, 2013
Enabling power: Education Act 1996, s. 537A (4) (5) (6). Issued: 29.05.2013. Made: 20.05.2013. Laid: 29.05.2013. Coming into force: 28.06.2013. Effect: S.I. 2009/1563 amended.
Arbuthnot, James
core  

Homologous expression and purification of human HAX‐1 for structural studies

open access: yesFEBS Open Bio, EarlyView.
This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley   +1 more source

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