Results 51 to 60 of about 5,042,874 (302)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Stress detection through prompt engineering with a general-purpose LLM

Acta Psychologica
Advancements in large language models (LLMs) have opened new avenues for mental health monitoring through social media analysis. In this study, we present an iterative prompt engineering framework that significantly enhances the performance of the ...
Nima Esmi, Asadollah Shahbahrami, Yasaman Nabati, Bita Rezaei, Georgi Gaydadjiev, Peter de Jonge   +5 more
doaj   +1 more source

Decision Model Research on Engineering Project Arrangement of Power Grid Enterprise Group Based on Input and Output Efficiency Evaluation

MATEC Web of Conferences, 2015
The engineering project arrangement of a large-scale Power Grid Enterprise Group confronts optimization problems on how to achieve efficient investment, how to achieve overall balance.
Lu Gang, Luan Hao, He Wan, Ma Yungao
doaj   +1 more source

Cross-Kerr-based information transfer processes

, 2005
The realization of nonclassical states is an important task for many applications of quantum information processing. Usually, properly tailored interactions, different from goal to goal, are considered in order to accomplish specific tasks within the ...
Bose, S., Cheong, Y. W., Kim, M. S., Lee, Jinhyoung, Ogden, C., Paternostro, M.   +5 more
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

ECNet is an evolutionary context-integrated deep learning framework for protein engineering

Nature Communications, 2021
Protein engineering is an active area of research in which machine learning has proven quite powerful. Here, the authors present a deep learning method that integrates both general and protein-specific sequence representations to improve the engineering ...
Yunan Luo, Guangde Jiang, Tianhao Yu, Yang Liu, Lam Vo, Hantian Ding, Yufeng Su, Wesley Wei Qian, Huimin Zhao, Jian Peng   +9 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Engineering Students' Citation Skills: Instructor Perspectives and Educational Implications

Issues in Science and Technology Librarianship
This article addresses the oft-noted gap between the amount of instruction students have received and the citation knowledge they demonstrate once they reach discipline-specific courses.
Kristy Kelly, Diana Park, Adam Lindsley, Laurie Bridges   +3 more
doaj   +1 more source

Targeting engineering synchronization in chaotic systems

, 2015
A method of targeting engineering synchronization states in two identical and mismatch chaotic systems is explained in details. The method is proposed using linear feedback controller coupling for engineering synchronization such as mixed synchronization,
Bhowmick, Sourav K., Ghosh, Dibakar
core   +1 more source