Results 71 to 80 of about 5,042,874 (302)
AAA+ protein unfoldases—the Moirai of the proteome
FEBS Letters, EarlyView.AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
Energy efficiency in civil engineering: analyzing world experience
MATEC Web of Conferences, 2018 There are consistent trends in the development of energy-saving technologies in civil engineering in almost all countries of the world. The article considers the main approaches to ensuring energy efficiency in in civil engineering, analyzes the ...
Bezdenezhnukh Tatiana +2 more
doaj +1 more source
Issues in Science and Technology Librarianship, 2009 This exploratory study reports on what engineering undergraduate students know and would like to learn about engineering information sources and access.
Zorana Ercegovac
doaj +1 more source
Analysis of the scientific production of the Spanish Software Engineering Community [PDF]
, 2015 Our group has been working on a report for the Spanish Society of Software Engineering and Software Development Technologies (SISTEDES) to provide a general overview of the Spanish scientific production and its contributions worldwide in the field of ...
Burgueño, Loli +2 more
core
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Teaching ethics to engineering undergraduates - lessons learned and a guide for lecturers: perspective from an English University [PDF]
, 2012 The issue of ethics within engineering profession has been gaining more and more importance due to globalisation, increasing awareness of sustainability and the fast changing business culture within engineering organisations.
Hasan, Reaz
core
GEO: Generative Engine Optimization
Proceedings of the 30th ACM SIGKDD Conference on Knowledge Discovery and Data MiningThe advent of large language models (LLMs) has ushered in a new paradigm of search engines that use generative models to gather and summarize information to answer user queries. This emerging technology, which we formalize under the unified framework of generative engines (GEs), can generate accurate and personalized responses, rapidly replacing ...
Pranjal Aggarwal +5 more
openaire +2 more sources
General chemistry for engineers [PDF]
Journal of Chemical Education, 1982 A logical way introduce polymers into the general chemistry course. From "The Goals of General Chemistry - A Symposium."
openaire +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source