Results 101 to 110 of about 3,454,963 (308)

Construindo pontes entre ciência e sociedade: divulgação científica sobre irradiação de alimentos

Brazilian Journal of Radiation Sciences, 2018
Food irradiation is a safe and effective preservation technique to eliminate insects and parasites and reduce disease-causing microorganisms. The process helps to inhibit sprouting and delay ripening, prolonging the shelf-life of fresh fruits and ...
Denise S. Levy, Gian Maria Agostino Angelo Sordi, Anna Lucia Casanas Haasis Villavicencio   +2 more
doaj   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

The threefold potential of environmental citizen science - Generating knowledge, creating learning opportunities and enabling civic participation

Biological Conservation, 2018
Abstract Citizen science offers significant innovation potential in science, society and policy. To foster environmental and conservation goals, citizen science can (i) generate new knowledge, (ii) enhance awareness raising and facilitate in-depth learning as well as (iii) enable civic participation.
Tabea Turrini, Daniel Dörler, Anett Richter, Florian Heigl, Aletta Bonn   +4 more
openaire   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Human dimensions of global environmental change: A review of frameworks and research gaps. [PDF]

, 2005
This review of current knowledge in, and development of, priorities for research into the human dimensions of global environmental change has been conducted to assist the Foundation for Research Science and Technology to formulate their research needs ...
Campbell, John, Gillespie, Alexander, Scrimgeour, Frank, Urich, Peter   +3 more
core   +1 more source

A Typology of Indigenous Engagement in Australian Environmental Management: Implications for Knowledge Integration and Social-ecological System Sustainability

Ecology and Society, 2012
Indigenous peoples now engage with many decentralized approaches to environmental management that offer opportunities for integration of Indigenous Ecological Knowledge (IEK) and western science to promote cultural diversity in the management of social ...
Rosemary Hill, Chrissy Grant, Melissa George, Catherine J. Robinson, Sue Jackson, Nick Abel   +5 more
doaj   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

How Environmental Attitudes interact with Cognitive Learning in a Science Lesson Module [PDF]

, 2016
As cognitive knowledge plays a major role in supporting proenvironmental behavior, identification of individual aspects related to knowledge acquisition is essential.
Bogner, Franz X., Schumm, Maximiliane
core   +2 more sources

Intermediary Effect of Digital Economy on Impact of the Fiscal Revenue and Expenditure Structure on Dual-Circulation Development Paradigm

International Journal of Crowd Science
In the context of dual-circulation development paradigm and high-quality economic growth in full swing, it is crucial to adjust the structure of fiscal revenue and expenditure to drive the crowd intelligence-driven digital economy’s development. From the
Yan Zhao, Xiaoya Kong, Jing Yang, Piotr Felisiak   +3 more
doaj   +1 more source

Survivin and Aurora Kinase A control cell fate decisions during mitosis

Molecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir, Shalitha Wickrama Arachchige, Sally P. Wheatley   +2 more
wiley   +1 more source