Results 21 to 30 of about 169,060 (266)
The chirality quantification is of great importance in structural biology, where the differences in proteins twisting can provide essentially different physiological effects.
Vladimir Bystrov +8 more
doaj +1 more source
Exploring Flexibility of Progesterone Receptor Ligand Binding Domain Using Molecular Dynamics. [PDF]
Progesterone receptor (PR), a member of nuclear receptor (NR) superfamily, plays a vital role for female reproductive tissue development, differentiation and maintenance.
Liangzhen Zheng +2 more
doaj +1 more source
An Extended Winged Helix Domain in General Transcription Factor E/IIEα [PDF]
Initiation of eukaryotic mRNA transcription requires melting of promoter DNA with the help of the general transcription factors TFIIE and TFIIH. Here we define a conserved and functionally essential N-terminal domain in TFE, the archaeal homolog of the large TFIIE subunit alpha.
Meinhart, A., Blobel, J., Cramer, P.
openaire +5 more sources
Evidence-Based Structural Model of the Staphylococcal Repressor Protein: Separation of Functions into Different Domains. [PDF]
Horizontal transfer of mobile genetic elements within Staphylococci is of high biomedical significance as such elements are frequently responsible for virulence and toxic effects.
Kinga Nyíri +4 more
doaj +1 more source
A Miniaturized Dual-Orbital-Angular-Momentum (OAM)–Mode Helix Antenna
Traditional helix antenna is firstly modified to radiate orbital angular momentum (OAM) wave, which has a compact size and an outstanding gain. Firstly, general principle of generating OAM by helix antenna is introduced.
Dang Weiguo +3 more
doaj +1 more source
Helix-formation and folding as studied in generalized-ensemble simulations [PDF]
Studying simple artificial peptides, we show that recently developed simulation techniques enable efficient investigations of secondary structure formation and folding in small peptides.
Alves, Nelson A., Hansmann, Ulrich H. E.
openaire +3 more sources
Discovery of novel helix binding sites at protein-protein interfaces
Protein-protein interactions (PPIs) play a key role in numerous biological processes. Many efforts have been undertaken to develop PPI modulators for therapeutic applications; however, to date, most of the peptide binders designed to target PPIs are ...
Wei Yang +3 more
doaj +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Correction of Constricted Ear – Case Report
Introduction. Congenital deformities of the outer ear are common; reported incidence are from 1:6000 to 1:6830 newborns. Multitude of corrective procedures are described in the literature. Purpose of the case study.
Ljubinka Damjanoska Krstikj +3 more
doaj +3 more sources
The content of fatty acids in the meat of snails by the action of heat processing
Increasing food production and improving their quality is one of the main problems facing the agro-industrial complex of Ukraine in modern conditions.
I. S. Danilova
doaj +1 more source

