Results 41 to 50 of about 174,885 (266)
On characterizations of g n-helices with Euler angles
Open MathematicsCurvature and torsion, in their most general forms, are defined in terms of Euler angle-based parametrization via the Cartan matrix, which leads to the Serret-Frenet equations.
Altinok Mesut, Kula Levent
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Sequence conservation of apolipoprotein A-I affords novel insights into HDL structure-function
Journal of Lipid Research, 2011 We performed alignment of apolipoprotein A-I (apoA-I) sequences from 31 species of animals. We found there is specific conservation of salt bridge-forming residues in the first 30 residues of apoA-I and general conservation of a variety of residue types ...
Denys Bashtovyy +3 more
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Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
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Beyond the binding site: the role of the β₂-β₃ loop and extra-domain structures in PDZ domains. [PDF]
PLoS Computational Biology, 2012 A general paradigm to understand protein function is to look at properties of isolated well conserved domains, such as SH3 or PDZ domains. While common features of domain families are well understood, the role of subtle differences among members of these
Stefano Mostarda +2 more
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FEBS Letters, 1996 The Id family of helix‐loop‐helix proteins function as negative regulators of DNA binding, basic helix‐loop‐helix proteins in the regulation of cell growth and differentiation. We report here on the identification of a 17 kDa variant of the 14 kDa Id‐3 protein termed Id‐3L (long version) which possesses a unique 60 amino acid carboxy‐terminus generated
Deed, Richard W. +2 more
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Generalized phantom helix states in quantum spin graphs
, 2023 In general, the summation of a set of sub-Hamiltonians cannot share a common eigenstate of each one, only if it is an unentangled product state, such as a phantom helix state in quantum spin system. Here we present a method, referred to as the building block method (BBM), for constructing possible spin-1/2 XXZ Heisenberg lattice systems possessing ...
Zhang, C. H., Shi, Y. B., Song, Z.
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Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
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Comparative evaluation of gears with different finishing processes using a shape deviation network [PDF]
MATEC Web of ConferencesIn general, the accuracy grade of manufactured gears is classified based on standards such as ISO 1328-1. However, tooth profile and helix deviations are usually evaluated individually using measurement data from each tooth flank, and methods for ...
Seo Yuichiro +5 more
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Molecular Oncology, EarlyView.Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez +5 more
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III-harmonic Curves in SL2ℝ˜\widetilde {{\rm{S}}{{\rm{L}}_2}\mathbb{R}} Space
Annals of the West University of Timisoara: Mathematics and Computer ScienceSome work has been done in the study of non-geodesic III-harmonic curves in some model spaces. In this paper, we study III-harmonic curves in SL2ℝ˜\widetilde {{\rm{S}}{{\rm{L}}_2}\mathbb{R}} space. We give necessary and su cient conditions for helices to
Senoussi Bendehiba
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