Results 51 to 60 of about 1,452,737 (303)

A Priori Error Estimates of Mixed Finite Element Methods for General Linear Hyperbolic Convex Optimal Control Problems

open access: yesAbstract and Applied Analysis, 2014
The aim of this work is to investigate the discretization of general linear hyperbolic convex optimal control problems by using the mixed finite element methods.
Zuliang Lu, Xiao Huang
doaj   +1 more source

Computational form-finding methods for fabric structures [PDF]

open access: yes, 2008
Form-finding is a process that determines the surface configuration of a fabric structure under prestress. This process can be carried out using a variety of numerical methods, of which the most common are (a) transient stiffness, (b) force density, and (
Lewis, W. J. (Wanda J.)
core   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Numerical simulation of fuzzy differential equations using general linear method and B-series

open access: yesAdvances in Mechanical Engineering, 2017
In this article, numerical simulation of fuzzy differential equations using general linear method is proposed. The significance of general linear method is derivation of algebraic order conditions of method using technique of rooted trees and B-series ...
Faranak Rabiei   +3 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

General Runge–Kutta–Nyström Methods for Linear Inhomogeneous Second-Order Initial Value Problems

open access: yesMathematics
In this paper, general Runge–Kutta–Nyström (GRKN) methods are developed and analyzed, tailored for second-order initial value problems of the form y″=Ly′+My+g(t), where L,M∈Rn×n are constant matrices with n≥1. The construction of embedded pairs of orders
Nadiyah Hussain Alharthi   +3 more
doaj   +1 more source

(α)-Stable Multi-Derivative GLM

open access: yesJournal of Algorithms & Computational Technology, 2015
This paper considers multi-derivative general linear methods and thus presents some second and third derivative general linear methods of orders 5, 7 and 10 in its output methods for computing the solution of stiff initial value problems in ordinary ...
R. I. Okuonghae, M. N. O. Ikhile
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

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