Results 71 to 80 of about 1,452,737 (303)
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Frontiers in Human Neuroscience, 2019 Functional near-infrared spectroscopy (fNIRS) research articles show a large heterogeneity in the analysis approaches and pre-processing procedures. Additionally, there is often a lack of a complete description of the methods applied, necessary for study
Paola Pinti +5 more
doaj +1 more source
GENERAL LINEAR METHODS FOR VOLTERRA [PDF]
, 2008 . A new class of numerical methods for Volterra integro-differential equations with memory is developed. The methods are based on the combination of general linear methods with compound quadrature rules.
Stefan Vandewalle, Chengjian Zhang
core
Global and Koopman modes analysis of sound generation in mixing layers [PDF]
, 2013 It is now well established that linear and nonlinear instability waves play a significant role in the noise generation process for a wide variety of shear flows such as jets or mixing layers.
X. Gloerfelt +7 more
core +1 more source
Electron transfer between complexes III and IV in S. cerevisiae mitochondrial membranes
FEBS Letters, EarlyView.Mitochondrial oxidative phosphorylation in S. cerevisiae mitoplasts is limited by complex IV catalytic capacity, rather than two‐dimensional cytochrome c diffusion. At physiological cytochrome c : supercomplex ratios at salinity equivalent to that of 20 mm monovalent salt, activity is maximized, indicating that this low ionic strength accurately mimics
Ana Paula Lobez +2 more
wiley +1 more source
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
, 2018 This paper concerns with the developing the most general schemes so-called Fuzzy General Linear Methods (FGLM) for solving fuzzy differential equations. The general linear methods (GLM) for ordinary differential equations are the middle state of two extreme extensions (linear multistep and Runge-Kutta methods) of the one step Euler method.
Farzi, Javad, Moradi, Afsaneh
openaire +2 more sources
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Matrix rank/inertia formulas for least-squares solutions with statistical applications
Special Matrices, 2016 Least-Squares Solution (LSS) of a linear matrix equation and Ordinary Least-Squares Estimator (OLSE) of unknown parameters in a general linear model are two standard algebraical methods in computational mathematics and regression analysis.
Tian Yongge, Jiang Bo
doaj +1 more source