Results 91 to 100 of about 26,321,511 (299)
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Comparative Study of Delay Discounting Rates in Alcohol and Opioid Dependence in Northern India
Indian Journal of Community MedicineBackground: The study of delay discounting (DD) in addictive disorders helps in understanding why an individual chooses addictive substances immediately over possible long-term gains.
Md Abdus Sabir +4 more
doaj +1 more source
GIScience & Remote Sensing, 2019 Tree height is essential for assessing carbon budgets and biodiversity. One of the most commonly used assessment methods is a field survey. However, this approach is extremely challenging for obtaining highly accurate estimates in forests with tall and ...
Chih-Hsin Chung +3 more
doaj +1 more source
Holistic Generalized Linear Models
Journal of Statistical Software34 pages, 2 figures, 4 ...
Benjamin Schwendinger +2 more
openaire +6 more sources
Robust Bayesian general linear models
NeuroImage, 2007 We describe a Bayesian learning algorithm for Robust General Linear Models (RGLMs). The noise is modeled as a Mixture of Gaussians rather than the usual single Gaussian. This allows different data points to be associated with different noise levels and effectively provides a robust estimation of regression coefficients.
Will D. Penny +2 more
openaire +3 more sources
Effects of aging on brain networks during swallowing: general linear model and independent component analyses. [PDF]
Sci Rep, 2021 Tae WS, Lee S, Choi S, Pyun SB.
europepmc +1 more source
Computer Automation of General-to-Specific Model Selection Procedures [PDF]
That econometric methodology remains in dispute partly reflects the lack of clear evidence on alternative approaches. This paper reconsiders econometric model selection from a computer-automation perspective, focusing on general-to-specific reduction ...
Hans-Martin Krolzig
core
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Robust Inference in Generalized Linear Models
Communications in Statistics - Simulation and Computation, 2016 Robust inference on the parameters in generalized linear models is performed using the weighted likelihood method. Two cases are considered: a case with replicated observations and a case with a single observation of the dependent variable for each combination of the explanatory variables.
Alqallaf, Fatemah, Agostinelli, Claudio
openaire +4 more sources
‘Guide and Prejudice’— How Argonautes recognize targets across domains of life
FEBS Letters, EarlyView.Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley +1 more source