Results 91 to 100 of about 1,299,612 (309)

Robust Inference in Generalized Linear Models

open access: yesCommunications in Statistics - Simulation and Computation, 2016
Robust inference on the parameters in generalized linear models is performed using the weighted likelihood method. Two cases are considered: a case with replicated observations and a case with a single observation of the dependent variable for each combination of the explanatory variables.
Alqallaf, Fatemah, Agostinelli, Claudio
openaire   +3 more sources

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Pricing in ecosystems: A generalized linear production model [PDF]

open access: yes
In this paper a method is developed to derive prices for natural goods from information about material and energy flows within ecosystems. The derivation is based on an analogy between ecological and economic systems: both systems are characterized by ...
Klauer, Bernd
core  

Teaching GLM Concepts: Explicating the Connections

open access: yesJournal of Methods and Measurement in the Social Sciences, 2015
The purpose of the present paper is to encourage textbook authors, quantitative instructors, curriculum writers, and software developers to move away from the use of isolated apparently disconnected analyses and instead move towards the use of the ...
Susan Troncoso Skidmore
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

The Case for Using the General Linear Model as a Unifying Conceptual Framework for Teaching Statistics and Psychometric Theory

open access: yesJournal of Methods and Measurement in the Social Sciences, 2015
The present paper argues for teaching statistics and psychometric theory using the GLM as a unifying conceptual framework. This helps students understand what analyses have in common, and also provides a firm grounding for understanding that more general
Bruce Thompson
doaj   +1 more source

Robust Bayesian general linear models

open access: yesNeuroImage, 2007
We describe a Bayesian learning algorithm for Robust General Linear Models (RGLMs). The noise is modeled as a Mixture of Gaussians rather than the usual single Gaussian. This allows different data points to be associated with different noise levels and effectively provides a robust estimation of regression coefficients.
Will D. Penny   +2 more
openaire   +3 more sources

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

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