In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Special Issue Introduction: Teaching the General Linear Model
Rafael Antonio Garcia, Melinda F Davis
doaj +1 more source
Testing for spatial heterogeneity in functional MRI using the multivariate general linear model [PDF]
Much current research in functional MRI employs multivariate machine learning approaches (e.g., support vector machines) to detect fine-scale spatial patterns from the temporal fluctuations of the neural signal.
Leech, Dennis, Leech, Robert
core
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
Comparative Study of Delay Discounting Rates in Alcohol and Opioid Dependence in Northern India
Background: The study of delay discounting (DD) in addictive disorders helps in understanding why an individual chooses addictive substances immediately over possible long-term gains.
Md Abdus Sabir +4 more
doaj +1 more source
Towards understanding the antagonistic activity of phytic acid against common foodborne bacterial pathogens using a general linear model. [PDF]
Boukhris I +7 more
europepmc +1 more source
RIPK4 function interferes with melanoma cell adhesion and metastasis
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
The tourism country’s competitiveness is important especially when countries strive for bigger market shares as European countries are. The COVID-19 pandemic has had devastating effects on tourism and the entire tourism industry must be rethinking and ...
Gabor Manuela Rozalia +2 more
doaj +1 more source
Improved physiological noise regression in fNIRS: A multimodal extension of the General Linear Model using temporally embedded Canonical Correlation Analysis. [PDF]
von Lühmann A +4 more
europepmc +1 more source

