Results 61 to 70 of about 1,179,697 (255)

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Improved cerebrovascular reactivity mapping using coherence weighted general linear model in the frequency domain. [PDF]

Neuroimage, 2023
Xu B, Vu C, Borzage M, González-Zacarías C, Shen J, Wood J.   +5 more
europepmc   +1 more source

Survivin and Aurora Kinase A control cell fate decisions during mitosis

Molecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir, Shalitha Wickrama Arachchige, Sally P. Wheatley   +2 more
wiley   +1 more source

Prediction of spirometry outcome in Croatian patients with chronic obstructive pulmonary disease

Monaldi Archives for Chest Disease
The current study offers an extensive examination of the influence of 29 diverse parameters on spirometry measurement variables in a cohort of 534 patients with chronic obstructive pulmonary disease (COPD) from five different centers in Croatia.
Erim Bešić, Davorka Muršić, Tajana Jalušić Glunčić, Jelena Ostojić, Sanda Škrinjarić-Cincar, Martina Dokoza, Nataša Karamarković Lazarušić, Miroslav Samaržija, Andrea Vukić Dugac   +8 more
doaj   +1 more source

A New Approach to the Formant Measuring Problem

Proceedings, 2019
Formants are characteristic frequency components in human speech that are caused by resonances in the vocal tract during speech production. They are of primary concern in acoustic phonetics and speech recognition.
Marnix Van Soom, Bart de Boer
doaj   +1 more source

Independent component analysis: a reliable alternative to general linear model for task-based fMRI. [PDF]

Front Psychiatry, 2023
Gkiatis K, Garganis K, Karanasiou I, Chatzisotiriou A, Zountsas B, Kondylidis N, Matsopoulos GK.   +6 more
europepmc   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

The Case for Using the General Linear Model as a Unifying Conceptual Framework for Teaching Statistics and Psychometric Theory

Journal of Methods and Measurement in the Social Sciences, 2015
The present paper argues for teaching statistics and psychometric theory using the GLM as a unifying conceptual framework. This helps students understand what analyses have in common, and also provides a firm grounding for understanding that more general
Bruce Thompson
doaj   +1 more source

Determinants of nutritional status among old age population in eastern Ethiopia: a general linear model approach. [PDF]

J Nutr Sci, 2022
Derbie L, Oumer A, Ayele K, Berhane A.
europepmc   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source