Results 61 to 70 of about 26,321,511 (299)

Association Between Individualized Education for Kidney Replacement Therapy Modality Selection and Peritoneal Dialysis Initiation: A Cross‐Sectional Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Peritoneal dialysis (PD) is an established home‐based kidney replacement therapy (KRT), but its uptake remains low in Japan. We evaluated whether individualized education in a dedicated outpatient clinic was associated with the initiation of PD.
Yasuko Ito, Ryuichi Yoshimura, Takaki Yamauchi, Yuta Funakoshi, Hirotaka Sonoda, Seiji Kobayashi, Hiroyuki Terawaki, Takafumi Ito   +7 more
wiley   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Analysis of variance components for genetic markers with unphased genotypes

Frontiers in Genetics, 2016
An ANOVA type general multi-allele (GMA) model was proposed in cite{Wang2014} on analysis of variance components for quantitative trait loci or genetic markers with phased or unphased genotypes.
Tao Wang
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, Volume 600, Issue 17, Page 2564-2578, September 2026.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Flexible scan statistic with a restricted likelihood ratio for optimized COVID-19 surveillance

Geospatial Health
Disease surveillance remains important for early detection of new COVID-19 variants. For this purpose, the World Health Organization (WHO) recommends integrating of COVID-19 surveillance with other respiratory diseases.
Ernest Akyereko, Frank B. Osei, Kofi M. Nyarko, Alfred Stein   +3 more
doaj   +1 more source

A variance shift model for detection of outliers in the linear mixed model

, 2010
A variance shift outlier model (VSOM), previously used for detecting outliers in the linear model, is extended to the variance components model.
Gogel, B. J., Gogel, B., Gumedze, F. N., Weham, S., Thompson, R., Welham, S. J., Gumedze, F.   +6 more
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

One missing value problem in Latin square design of any order: Exact analysis of variance

Cogent Engineering, 2017
This research proposes a simplified exact approach based on the general linear model for solving the K × K Latin square design (LSD) with one replicate and one missing value, given the lack of ready-made mathematical formulas for the sub-variance.
Kittiwat Sirikasemsuk, Kanogkan Leerojanaprapa   +1 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Generalized Linear Rule Models

CoRR, 2019
This paper considers generalized linear models using rule-based features, also referred to as rule ensembles, for regression and probabilistic classification. Rules facilitate model interpretation while also capturing nonlinear dependences and interactions.
Dennis Wei, Sanjeeb Dash, Tian Gao, Oktay Günlük   +3 more
openaire   +3 more sources