Results 121 to 130 of about 7,005,393 (307)
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Enforcement Problems and Secondary Markets [PDF]
There is a large and growing literature that studies the effects of weak enforcement institutions on economic performance. This literature has focused almost exclusively on primary markets, in which assets are issued and traded to improve the allocation ...
Alberto Martin +2 more
core
Molecular Oncology, EarlyView.Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source
Why Left-handers/footers are overrepresented in some sports? [PDF]
Montenegrin Journal of Sports Science and Medicine, 2014 Left-handers/footers are found with disproportionately more frequency in many interactive sports compared to the general po¬pu¬lation. In ıorder to point out this issue, we firstly mentioned about handedness in general and secondly the origin of ...
Selcuk Akpinar, Bilal Bicer
doaj
Overview of molecular signatures of senescence and associated resources: pros and cons
FEBS Open Bio, EarlyView.Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas +6 more
wiley +1 more source
A Phenomenology of the Practice of Music Therapy with Children [PDF]
, 2018 Music therapy has been demonstrated as an effective mode of therapeutic intervention for children in recent literature. There is extensive research suggesting benefits for various populations of children, namely: children in the neonatal intensive care ...
Tortorello, Shelby
core +1 more source
SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1
FEBS Open Bio, EarlyView.Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl +13 more
wiley +1 more source
IEEE AccessGenerative Artificial Intelligence (GenAI) and Large Language Models (LLMs) are transforming research methodologies, including Systematic Literature Reviews (SLRs). While traditional, human-led SLRs are labor-intensive, AI-driven approaches promise efficiency and scalability.
openaire +2 more sources
FEBS Open Bio, EarlyView.We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies +3 more
wiley +1 more source
The Economics of International Differences in Educational Achievement [PDF]
An emerging economic literature over the past decade has made use of international tests of educational achievement to analyze the determinants and impacts of cognitive skills. The cross-country comparative approach provides a number of unique advantages
Hanushek, Eric A., Woessmann, Ludger
core +3 more sources