Results 121 to 130 of about 2,182,908 (305)

Islands, Island Studies, Island Studies Journal [PDF]

open access: yes, 2006
Islands are sites of innovative conceptualizations, whether of nature or human enterprise, whether virtual or real. The study of islands on their own terms today enjoys a growing and wide-ranging recognition.
Baldacchino, Godfrey   +1 more
core  

Citation Analysis and Grey Literature: Stakeholders in the Grey Circuit

open access: yes, 2012
The goal of this research project is to learn more about the expanding field of information known as "grey literature". Citation analysis allows one the possibility to follow the work of the authors in the GL-Conference series, as well as authors whom ...
Schöpfel, Dr. J. (INIST-CNRS)   +4 more
core   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

Early American Studies Now: A Polemic from Literary Studies [PDF]

open access: yes, 2013
This polemic stages a critique of (often presentist) political readings of early American novels dominant in Early American Studies (and American Studies more generally), proposing a return to aesthetic questions informed by systems theory ...
Schweighauser, Philipp
core  

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

open access: yesMolecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi   +11 more
wiley   +1 more source

Literature Study on the Contribution of General Practitioners in Health Promotion and Prevention Efforts

open access: yesNusantara Sehat: Jurnal Kesehatan Indonesia
ABSTRACT This study aims to explore and synthesize the contributions of general practitioners (GPs) in promotive and preventive healthcare, emphasizing their role in strengthening primary health systems and community well-being. Using a qualitative descriptive approach through literature study, data were collected from scientific journals, books, and ...
null Putri Raudhatul Jannah   +1 more
openaire   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

XII - Literature 1780-1830: The Romantic Period

open access: yes, 2016
First paragraph: Two of the major themes to come out of the works published in 2014 in the field of Romantic general and prose writing are those of local, national, and global identities, and questions of selfhood.
Ward, Matthew   +4 more
core   +1 more source

Why Left-handers/footers are overrepresented in some sports? [PDF]

open access: yesMontenegrin Journal of Sports Science and Medicine, 2014
Left-handers/footers are found with disproportionately more frequency in many interactive sports compared to the general po¬pu¬lation. In ıorder to point out this issue, we firstly mentioned about handedness in general and secondly the origin of ...
Selcuk Akpinar, Bilal Bicer
doaj  

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