Results 101 to 110 of about 30,342,537 (290)
Comparing the paths of Hedgehog release in artificial and natural settings
FEBS Letters, EarlyView.Hh morphogens require solubilization factors to overcome their tight association with the plasma membrane and signal to distant cells, but the precise functions of these factors are controversial. Here, we use published in vivo observations as the most relevant evidence to test their suggested functions and discuss contradictions and gaps between in ...
Janna Puschmann, Kay Grobe
wiley +1 more source
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
Nusantara Sehat: Jurnal Kesehatan IndonesiaABSTRACT This study aims to explore and synthesize the contributions of general practitioners (GPs) in promotive and preventive healthcare, emphasizing their role in strengthening primary health systems and community well-being. Using a qualitative descriptive approach through literature study, data were collected from scientific journals, books, and ...
null Putri Raudhatul Jannah +1 more
openaire +1 more source
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Prevalence of fibromyalgia: literature review update
Revista Brasileira de ReumatologiaThe present study aimed to update the literature review on the prevalence of fibromyalgia published in 2006. A bibliographical survey was carried out from 2005 to 2014 in the MEDLINE, Web of Science, Embase, LILACS and SciELO databases and 3274 records ...
Amelia Pasqual Marques +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
wiley +1 more source
A Bibliometric Analysis of Political Science Research on a Global Scale
Akademik İncelemeler DergisiThis research aims to contribute to a macro-level understanding of the intellectual foundations of the field of political science by examining it in depth through bibliometric analysis and discovering the epistemological insights hidden in it, as well as
Emre Aydilek
doaj +1 more source
Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
Acta PsychologicaThe psychological functions of Chinese literature have received limited empirical attention despite its central role in cultural transmission. The present research examined how engagement with different genres of Chinese literature relates to social ...
Xiaoqing Zhao, Chunying Xu, Yan Zhang
doaj +1 more source
Development of investment securities in the United States
, 1894 Thesis (B.S.)--Massachusetts Institute of Technology, Dept. of General Studies, 1894.by C.R.
Boss, C. R. (Charles Royce), b. 1871
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