Results 91 to 100 of about 7,005,393 (307)

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

Carotid endarterectomy: review of 10 years of practice of general and locoregional anesthesia in a tertiary care hospital in Portugal

Revista Brasileira de Anestesiologia, 2015
BACKGROUND: Retrospective and prospective randomized studies have compared general and locoregional anesthesia for carotid endarterectomy, but without definitive results.OBJECTIVES: Evaluate the incidence of complications (medical, surgical, neurological,
Mercês Lobo, Joana Mourão, Graça Afonso   +2 more
doaj   +1 more source

[Review of] Jack Kugelmass, ed. Between Two Worlds: Ethnographic Essays on American Jewry [PDF]

, 1990
This volume contains twelve varied, academically insightful, and often just plain entertaining chapters, along with the editor\u27s lengthy and instructive introduction.
Gradwohl, David M.
core   +1 more source

Exact solutions of effective-mass Schrodinger equations

, 2002
We outline a general method for obtaining exact solutions of Schr\"{o}dinger equations with a position dependent effective mass and compare the results with those obtained within the frame of supersymmetric quantum theory.
BEŞIRE GÖNÜL, BÜLENT GÖNÜL, FATMA ÜZGÜN, OKAN ÖZER, Plastino A. R., Plastino A. R., Puente A.   +6 more
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Dicţionarul general al literaturii române – enciclopedie a literaturii și culturii naționale [PDF]

Revista de Istorie și Teorie Literară, 2019
The most comprehensive, representative and imposing lexicographic work of the Romanian literary history and criticism, the General Dictionary of Romanian Literature is a real encyclopedia of our national literature and culture.
Laurențiu Hanganu
doaj  

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Prevalence of fibromyalgia: literature review update

Revista Brasileira de Reumatologia
The present study aimed to update the literature review on the prevalence of fibromyalgia published in 2006. A bibliographical survey was carried out from 2005 to 2014 in the MEDLINE, Web of Science, Embase, LILACS and SciELO databases and 3274 records ...
Amelia Pasqual Marques, Adriana de Sousa do Espírito Santo, Ana Assumpção Berssaneti, Luciana Akemi Matsutani, Susan Lee King Yuan   +4 more
doaj   +1 more source

Complexity results and exact algorithms for robust knapsack problems. [PDF]

This paper studies the robust knapsack problem, for which solutions are, up to a certain point, immune to data uncertainty. We complement the works found in the literature where uncertainty affects only the profits or only the weights of the items by ...
Leus, Roel, Talla Nobibon, Fabrice
core