Results 91 to 100 of about 30,342,537 (290)

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Literature Study Of Chamomile ( Matricaria Chamomilla ) For Generalized Anxiety Disordered

ULIL ALBAB : Jurnal Ilmiah Multidisiplin
Chamomile ( Matricaria chamomilla ) is one of the most widely used herbal medicines worldwide. Scientific evidence is needed to increase the use of chamomile in treating generalized anxiety disorder . This study aims to find out information from various scientific publications regarding the benefits of chamomile ( Matricaria chamomilla ) for ...
Suhendriyo Suhendriyo, null Fadila Anisa Perwito, null Susilo Yulianto   +2 more
openaire   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

FEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux, Christian Lévêque, Fodil Azzaz, Marion Sangiardi, Sarosh R Irani, Michael Seagar, Jacques Fantini, Oussama El Far   +7 more
wiley   +1 more source

Barriers, enablers and initiatives for uptake of advance care planning in general practice: a systematic review and critical interpretive synthesis

BMJ Open, 2019
Objectives How advance care planning (ACP) is conceptualised in Australia including when, where and how ACP is best initiated, is unclear. It has been suggested that healthcare delivered in general practice provides an optimal setting for initiation of ...
Joel Rhee, Lucie Walters, Jo Risk, Leila Mohammadi, Paul R Ward   +4 more
doaj   +1 more source

The ubiquitin system in normal and infected germinal center B cells

FEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis, Lesly Mejia, Emily K Moser   +2 more
wiley   +1 more source

Smaller is better: nanobodies meet NMR

FEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

The Concept of Generation in the Study of Twenty-First Century Mexican Literature: Usefulness and Limitations

Lingüística y Literatura, 2018
This article analyzes the concept of generation as a methodological tool for contemporary literary research, advancing its use to characterize aesthetic trends in the artistic production of diverse groups of coetaneous writers. By providing a cultural history of the uses of the category in Mexican literary studies, it examines the applicability and ...
openaire   +2 more sources

Technological Spillovers from Foreign Direct Investment—A Survey

Asian Development Review, 2003
Increased foreign direct investment (FDI) flows have stimulated intensive debate and research on the impact of FDI on host economies. This paper surveys the substantial literature exploring FDI and spillover effects, summarizes the main findings from ...
Emma Xiaoqin Fan
doaj   +1 more source

Diabetic Ketoacidosis Associated With Second Generation Antipsychotics: A Case Study and Review of Literature

Psychiatry Investigation
Objective Second-generation antipsychotics (SGAs) have revolutionized the treatment of psychiatric disorders, but are associated with significant metabolic risks, including diabetes and hyperglycemic crises. This review explores the complex interplay between antipsychotics, diabetes, and hyperglycemic crises, highlighting the mechanisms underlying SGA ...
Heewon Bae, Ji Hyun Lee, Sungsuk Je, Seung-Hoon Lee, Hayun Choi   +4 more
openaire   +2 more sources

DNA ligase LigE increases bacterial transformation with damaged extracellular DNA

FEBS Letters, EarlyView.
The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan, Avi Singh, Shrawani Weralupe Gamladdalage, Joanna Hicks, Adele Williamson   +4 more
wiley   +1 more source