Results 81 to 90 of about 30,342,537 (290)

The Speech Behaviour of Kazakhstani Youth in the Context of Interethnic Communication

Journalism and Media
This article explores the features of speech practices of young people in Kazakhstan in the conditions of interaction between Kazakh, Russian, and English, taking into account the influence of the digital environment and modern socio-cultural factors ...
Sholpan Zharkynbekova, Zukhra Shakhputova, Olga Anichshenko, Zhazira Agabekova   +3 more
doaj   +1 more source

THE CONTRIBUTION OF THE POST-PARTITION GENERATION TO HINDI LITERATURE: AN ANALYTICAL STUDY

International Journal of Research -GRANTHAALAYAH
The Partition of India (1947) was a watershed event that not only altered the political geography but also profoundly impacted cultural, social, and literary structures. This historic tragedy forced millions to grapple with displacement, violence, insecurity, and crises of identity.
Priya Chandwani, Neelam Singh
openaire   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

The role of pedagogical knowledge base, creativity, and resilience in shaping EFL teachers’ self-efficacy

Frontiers in Education
Teacher self-efficacy is essential for effective English as a Foreign Language (EFL) teaching, particularly in Kazakhstan's multilingual educational environment. This study examined the relationships between pedagogical knowledge base, teacher resilience,
Kuralay Kenzhekanova, Dameli Kapanova, Karlygash Dyussupbayeva, Akbilek Mynbayeva, Aray Rakisheva   +4 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

FEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

Co-location of seaweed farming with offshore wind energy: a quick scoping review

Frontiers in Marine Science
Seaweed farming is increasingly recognized as a sustainable marine resource management opportunity, but it also poses socioeconomic and environmental risks that require careful evaluation.
Brianna Coffey, Cortni Borgerson, Pankaj Lal, Colette J. Feehan   +3 more
doaj   +1 more source

Do patients with long-term side effects of cancer treatment benefit from general practitioner support? A literature review

International Journal of Integrated Care, 2015
Background: Alongside specialist cancer clinics, general practitioners have an important role in cancer patients’ follow-up care, yet no literature summarises the nature, extent and impact of their involvement.
Irene Ngune, Moyez Jiwa, Alexandra McManus, Jeff Hughes   +3 more
doaj   +1 more source