Results 81 to 90 of about 2,182,908 (305)

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Co-location of seaweed farming with offshore wind energy: a quick scoping review

Frontiers in Marine Science
Seaweed farming is increasingly recognized as a sustainable marine resource management opportunity, but it also poses socioeconomic and environmental risks that require careful evaluation.
Brianna Coffey, Cortni Borgerson, Pankaj Lal, Colette J. Feehan   +3 more
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Systematic quantitative literature review: Reviewing interdisciplinary literature on host-children

, 2019
The United Nations Sustainable Development Goals (UNSDG) aims to protect and eliminate all forms of child labour by 2025 (United Nations, 2018). According to the International Labour Organization (2002), roughly 19 million workers in tourism-related ...
Khoo-Lattimore, Catheryn, Yang, Chiao Ling, Yang, Mona Ji Hyun   +2 more
core  

In search of the right literature search engine(s)

, 2011
*Background* Collecting scientific publications related to a specific topic is crucial for different phases of research, health care and ‘effective text mining’. Available bio-literature search engines vary in their ability to scan
Mohammed Farouk, Darshan S. Chandrashekar, Kshitish K. Acharya, Samudyata V, Akhilesh K. Bajpai, Akhilesh Bajpai, Greta Kasliwal, ArunNehru KP, Neelima Chitturi, Sreelakshmi KS, Darshan Chandrashekar, Pranami Bora, Deepti H, Sravanthi Davuluri, Haritha Haridas, Kshitish Acharya   +15 more
core   +1 more source

The Many Faces of Nicknames

Names, 1990
Despite a vast scholarly literature on general naming practices, the serious investigation of nicknaming has barely begun. Pertinent literature lies thinly and sporadically scattered throughout the journals of social science disciplines, with most ...
Theodore J. Holland
doaj   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Clashing Cultures? Linking Literature and Hypertext at Post-16

, 2007
This paper argues that new digital genres clash with notions of a ‘traditional’ version of English, as represented in post-16 Advanced Level Literature exam courses in England. This argument is set within the context of an ongoing political imperative to
Matthewman, Sasha
core  

Cancer diagnosed by emergency admission in England: an observational study using the general practice research database. [PDF]

, 2013
BACKGROUND: Patients diagnosed with cancer by the emergency route often have more advanced diseases and poorer outcomes. Rates of cancer diagnosed through unplanned admissions vary within and between countries, suggesting potential inconsistencies in the
Majeed, Azeem, Paul Aylin, Bottle, Alex, Tsang, Carmen, Aylin, Paul, Alex Bottle, Azeem Majeed, Carmen Tsang   +7 more
core   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source