Results 71 to 80 of about 2,182,908 (305)

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Families, life events and family service delivery [PDF]

open access: yes, 2012
Life events or transitions are understood to be circumstances that have an unsettling element for individuals (and from a systemic perspective, for family members also).
Lixia Qu   +3 more
core  

The Speech Behaviour of Kazakhstani Youth in the Context of Interethnic Communication

open access: yesJournalism and Media
This article explores the features of speech practices of young people in Kazakhstan in the conditions of interaction between Kazakh, Russian, and English, taking into account the influence of the digital environment and modern socio-cultural factors ...
Sholpan Zharkynbekova   +3 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

The Sticky Temptation of Poetry

open access: yes, 2015
Sometime around 1900, a fundamental shift occurred in the way animals were represented in works of Western literature, art, and philosophy. Authors began to write about animals in a way that was unheard-of or even unimaginable in previous epochs ...
Driscoll, K.   +2 more
core   +1 more source

Barriers, enablers and initiatives for uptake of advance care planning in general practice: a systematic review and critical interpretive synthesis

open access: yesBMJ Open, 2019
Objectives How advance care planning (ACP) is conceptualised in Australia including when, where and how ACP is best initiated, is unclear. It has been suggested that healthcare delivered in general practice provides an optimal setting for initiation of ...
Joel Rhee   +4 more
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Centre for Australian Language and Literature Studies (CALLS) Yearbook No. 9 (1997-1998)

open access: yes, 2012
1997 and 1998 were expansive years for CALLS. It was decided at the Annual General Meeting in December 1997 to pursue a new vision for the Centre, to broaden its activities by embracing all the disciplines which come under the heading of Australian ...
O'Brien, Carmel, McPherson, Joanne
core  

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Technological Spillovers from Foreign Direct Investment—A Survey

open access: yesAsian Development Review, 2003
Increased foreign direct investment (FDI) flows have stimulated intensive debate and research on the impact of FDI on host economies. This paper surveys the substantial literature exploring FDI and spillover effects, summarizes the main findings from ...
Emma Xiaoqin Fan
doaj   +1 more source

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