Results 101 to 110 of about 3,727,363 (257)
Molecular Oncology, EarlyView.CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir +12 more
wiley +1 more source
The content of general practice in Malta : a pilot study comparing health centre and private practice in Malta with each other and with general practice (as reported for other countries) [PDF]
, 1989 The effective planning of a system and the training of personnel to run it requires accurate data regarding the use to be made of the system. For a health care system such data, apart from actual numbers of patients, will include age/sex distribution ...
Agius Muscat, Hugo, Carabott, Paul
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Molecular Oncology, EarlyView.A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He +8 more
wiley +1 more source
Biophotonics: a marriage of sciences [PDF]
, 2002 Biophotonics denotes a combination of biology and photonics, with photonics being the science and technology of generation, manipulation, and detection of photons, quantum units of light.
Girkin, J.M.
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Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
آموزش پزشکی, 2018 BACKGROUND AND OBJECTIVE: Doing and writing the qualified thesis could be considered as the onset of the research proceeding and formation of academic identity of students.
Mohammad rasoul Khazaee +3 more
doaj
Functional neurological disorder mimicking stroke: A case report
Clinical Case ReportsKEY CLINICAL MESSAGE Even in the era of technology‐guided medicine, the clinician must integrate into his daily practice a careful anamnesis and physical examination to be conducted within a close doctor–patient relationship. All these elements, together
G. Venturini, C. Sarti
doaj +1 more source
Uninsured and Dying Because of It: Updating the Institute of Medicine Analysis on the Impact of Uninsurance on Mortality [PDF]
, 2008 The absence of health insurance creates a range of consequences, including lower quality of life, increased morbidity and mortality, and higher financial burdens.
Stan Dorn
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Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
kurz und kn@pp news : No. 16 [engl. Fassung] [PDF]
, 2009 * Cooperation between "jeder-fehlerzaehlt.de" and the Techniker statutory insurance company * "PRIoritising multiple medication in multi-morbid patients" – PRIMUM-Pilot study gets off to successful start * New work area: Quality promotion and ...
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