Results 101 to 110 of about 14,404,861 (385)

Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma

open access: yesMolecular Oncology, EarlyView.
GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski   +19 more
wiley   +1 more source

Diagnosis and Treatment Protocol for COVID-19 Patients (Tentative 9th Version)

open access: yes​​​​​​​​Infectious Diseases & Immunity, 2022
The General Office of National Health Commission & the General Office of National Administration of Traditional Chinese Medicine   +1 more
doaj   +1 more source

Continuous renal replacement therapy for lithium toxicity: A worthy treatment to avoid intradialytic hypotension and vasopressors

open access: yesClinical Case Reports
Key Clinical Message While intermittent hemodialysis (HD) is the most efficient method of removing lithium in patients with lithium toxicity, continuous renal replacement therapy is an acceptable alternative in the setting of intradialytic hypotension ...
Pooya Zardoost   +6 more
doaj   +1 more source

Program development and initial experiences with the online class “Erste Hilfe Kasten – Allgemeinmedizin”

open access: yesGMS Journal for Medical Education
Objective: This project aims to provide doctors in postgraduate training (ÄiW) in general medicine with business knowledge of practice management through a modular training program within an e-learning environment, thereby reducing important barriers to ...
Seiler, Sabine   +3 more
doaj   +1 more source

A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner

open access: yesMolecular Oncology, EarlyView.
We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp   +13 more
wiley   +1 more source

A personalist-phenomenological model of general resurrection in light of current science and medicine [PDF]

open access: yes, 2018
I have argued that the central Christian doctrine of general resurrection (with particular reference to the Pauline corpus) can and should be understood in a scientifically and philosophically informed context, and have proposed a personalist ...
Danielyan, Edgar
core  

Reasons for Preferring Ayurveda [PDF]

open access: yes, 2010
South Asia in general, and India specifically, are regions with immense diversity in culture and language. Because of this conversations about medicine between doctors and patients takes different forms from one region to another. This is especially true
Joshi, Himanshu   +3 more
core   +1 more source

Hands-on Clinical Clerkship at the Department of General Medicine in a University Hospital Improves Medical Students’ Self-Evaluation of Skills of Performing Physical Examinations and Informed Consent: A Questionnaire-Based Prospective Study

open access: yesInternational Journal of General Medicine, 2022
Yoshinori Tokushima,1,2 Masaki Tago,1,2 Midori Tokushima,1,3 Shun Yamashita,1 Yuka Hirakawa,1 Hidetoshi Aihara,1 Naoko E Katsuki,1 Motoshi Fujiwara,1 Shu-ichi Yamashita1 1Department of General Medicine, Saga University Hospital, Saga, Japan; 2Community ...
Tokushima Y   +8 more
doaj  

Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias   +12 more
wiley   +1 more source

short @nd sweet news : Nr. 9 [PDF]

open access: yes, 2007
* Change the Date: 1st Frankfurt General Practice Day * Summer Symposium of the Praxissiegel Foundation on July 6, 2007 * Revamp of the course "Introduction to Clinical Medicine" * Summer celebration for practice participants in the ...

core  

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