Results 101 to 110 of about 14,798,231 (416)

Circulating tumor DNA (ctDNA) trajectories predict survival in trifluridine/tipiracil‐treated metastatic colorectal cancer patients

open access: yesMolecular Oncology, EarlyView.
The authors applied joint/mixed models that predict mortality of trifluridine/tipiracil‐treated metastatic colorectal cancer patients based on circulating tumor DNA (ctDNA) trajectories. Patients at high risk of death could be spared aggressive therapy with the prospect of a higher quality of life in their remaining lifetime, whereas patients with a ...
Matthias Unseld   +7 more
wiley   +1 more source

Poncet's disease: An uncommon presentation of a common disease in Sudan

open access: yesClinical Case Reports, 2023
Key Clinical Message Poncet's disease is an acute onset reactive polyarthritis associated with tuberculosis infection. Although uncommon, the diagnosis should be considered among patients presenting with symmetrical polyarthritis in tuberculosis‐endemic ...
Abdalla Mohamed Abdalla Mohamedali   +6 more
doaj   +1 more source

Network medicine framework reveals generic herb-symptom effectiveness of Traditional Chinese Medicine [PDF]

open access: yesarXiv, 2022
Traditional Chinese medicine (TCM) relies on natural medical products to treat symptoms and diseases. While clinical data have demonstrated the effectiveness of selected TCM-based treatments, the mechanistic root of how TCM herbs treat diseases remains largely unknown. More importantly, current approaches focus on single herbs or prescriptions, missing
arxiv  

General Medicine and Hospital Medicine: The Janus of Internal Medicine [PDF]

open access: yesJournal of General Internal Medicine, 2017
In this issue of JGIM, Miller and colleagues draw attention to important trends in the evolution of academic general internal medicine.1 By examining the membership of the Society of General Internal Medicine (SGIM), they provide a snapshot not only of the Society, but also the trajectory of academic internal medicine.
Vineet Chopra, Laurence F. McMahon
openaire   +3 more sources

Predicting 30-Day Readmissions: Performance of the LACE Index Compared with a Regression Model among General Medicine Patients in Singapore

open access: yesBioMed Research International, 2015
The LACE index (length of stay, acuity of admission, Charlson comorbidity index, CCI, and number of emergency department visits in preceding 6 months) derived in Canada is simple and may have clinical utility in Singapore to predict readmission risk.
L. Low   +6 more
semanticscholar   +1 more source

Integrative analysis of circulating tumor cells (CTCs) and exosomes from small‐cell lung cancer (SCLC) patients: a comprehensive approach

open access: yesMolecular Oncology, EarlyView.
This study simultaneously investigated circulating tumor cells (CTCs) and exosomes from small‐cell lung cancer (SCLC) patients. The elevated expression of JUNB and CXCR4 in CTCs was a poor prognostic factor for SCLC patients, whereas exosomal overexpression of these biomarkers revealed a high discrimination ability of patients from healthy individuals,
Dimitrios Papakonstantinou   +13 more
wiley   +1 more source

Listeria peritonitis in a patient on hemodialysis for end‐stage renal disease secondary to lupus nephritis—a case report

open access: yesClinical Case Reports, 2023
Key Clinical Message Patients with a recent history of peritoneal dialysis catheter removal in the setting of immunosuppression should be monitored for rare Listeria bacterial peritonitis.
Victor Frederick Cox   +3 more
doaj   +1 more source

Evaluation of potential drug - drug interactions in general medicine ward of teaching hospital in southern India.

open access: yesJournal of clinical and diagnostic research : JCDR, 2015
BACKGROUND Polypharmacy is considered as one of the major risk factors in precipitation of drug-drug interactions (DDIs). Patient population at high risk include the elderly and patients with co morbidities as they are usually prescribed with more number
Akram Ahmad   +7 more
semanticscholar   +1 more source

Abstracts from the 2020 Annual Meeting of the Society of General Internal Medicine

open access: yesJournal of general internal medicine, 2020
s from the 2020 Annual Meeting of the Society of General Internal Medicine "J OURNEY OF A THOUSAND MILES” CHALLENGES ENCOUNTERED BY INTERNATIONAL MEDICAL GRADUATES AND COMPARATIVE PROBLEMS FACED BY AMERICAN GRADUATES DURING INTERNAL MEDICINE RESIDENCY ...
Sarah Roberts   +18 more
semanticscholar   +1 more source

Obesity alters the fitness of peritumoral adipose tissue, exacerbating tumor invasiveness in renal cancer through the induction of ADAM12 and CYP1B1

open access: yesMolecular Oncology, EarlyView.
Tumor microenvironment drives cancer formation and progression. We analyzed the role of human cancer‐associated adipocytes from patients with renal cell carcinoma (RCC) stratified as lean, overweight, or obese. RNA‐seq demonstrated that, among the most altered genes involved in the tumor–stroma crosstalk, are ADAM12 and CYP1B1, which were proven to be ...
Sepehr Torabinejad   +13 more
wiley   +1 more source

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