Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Background The electronic health record (EHR) of the general physician (GP) is an important tool that can be used to assess and improve the quality of healthcare.
Steve Van den Bulck +9 more
doaj +1 more source
Trends in sexually transmitted infections in general practice 1990-2000: population based study using data from the UK general practice research database [PDF]
Objective: To describe the contribution of primary care to the diagnosis and management of sexually transmitted infections in the United Kingdom, 1990-2000, in the context of increasing incidence of infections in genitourinary medicine clinics ...
Brook, M.G. +13 more
core
By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source
Background Collaborative care approaches between general practitioners (GPs) and pharmacists have received international recognition for medication optimization and deprescribing efforts.
Navina Gerlach +6 more
doaj +1 more source
The content of general practice in Malta : a pilot study comparing health centre and private practice in Malta with each other and with general practice (as reported for other countries) [PDF]
The effective planning of a system and the training of personnel to run it requires accurate data regarding the use to be made of the system. For a health care system such data, apart from actual numbers of patients, will include age/sex distribution ...
Agius Muscat, Hugo, Carabott, Paul
core
Never events in UK general practice: a survey of the views of general practitioners on their frequency and acceptability as a safety improvement approach [PDF]
Background: Never events (NEs) are serious preventable patient safety incidents and are a component of formal quality and safety improvement (Q&SI) policies in the United Kingdom and elsewhere.
Alam, Rahul +6 more
core +2 more sources
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Choice and the composition of general practice patient registers [PDF]
Choice of general practice (GP) in the National Health Service (NHS), the UKs universal healthcare service, is a core element in the current trajectory of NHS policy. This paper uses an accessibility-based approach to investigate the pattern of patient
Lewis, D., Longley, P., Mateos, P.
core
Primary Care Staff's Views and Experiences Related to Routinely Advising Patients about Physical Activity. A Questionnaire Survey [PDF]
Background: United Kingdom public health policy has recently re-emphasised the role of primary health care professionals in tackling increasing levels of physical inactivity within the general population.
A Steptoe +36 more
core +4 more sources

