Treatment of heart failure in Dutch general practice. [PDF]
, 2006 Contains fulltext : 51093.pdf ( ) (Open Access)BACKGROUND: To study the relation between the prescription rates of selected cardiovascular drugs (ACE-inhibitors and Angiotensin receptor blockers, beta-blockers, diuretics, and ...
van der Zee Jouke +20 more
core +2 more sources
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Access to general practice in England: political, theoretical, and empirical considerations [PDF]
, 2016 Access to general practice services in England has been a prominent theme in recent issues of the BJGP. Simpson and colleagues1 outlined the historical context of current policy to extend practice opening hours in the evenings and at weekends.
Gunning, Elinor J +3 more
core +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
General practice activity in Australia 2014–15 [PDF]
, 2015 This is the 17th annual report and the 38th book in the General Practice Series from the BEACH (Bettering the Evaluation and Care of Health) program, a continuous national study of general practice activity in Australia.Australian Government Department ...
Bayram, Clare +10 more
core
Comparison of Country and Metropolitan General Practice, 1990-1991
, 2019 The comparison of country and metropolitan general practice was intended to provide a description of country general practice in Australia. It was also intended to determine the extent to which country and metropolitan general practice differ in terms of
Britt, Helena, Bridges-Webb, Charles
core +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Diagnosing dementia in Dutch general practice: a qualitative study of GPs' practices and views
, 2016 GPs play an important role in recognising the symptoms of dementia; however, little is known about how they perceive their actual and future role in diagnosing dementia.
Pols, Jeannette +3 more
core +1 more source
Disentangling the concept of “the complex older patient” in general practice: a qualitative study [PDF]
, 2016 Background: The rising life expectancy in the developed world leads to an increase in the number of older patients and the complexity of their complaints in general practice.
O. R. Maarsingh +9 more
core +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source