Results 121 to 130 of about 1,223,026 (285)

Dose‐dependent induction of epithelial‐mesenchymal transition in 3D melanoma models by non‐thermal plasma treatment

open access: yesMolecular Oncology, EarlyView.
Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop   +10 more
wiley   +1 more source

Inextendibilty of the Maximal Global Hyperbolic Development in Electrogowdy spacetimes

open access: yesEPJ Web of Conferences, 2013
The problem of determinism in General Relativity appears even if one assumes that the spacetime is globally hyperbolic, i.e. that it contains a hypersurface that is intersected by any causal curve exactly once.
Nungesser Ernesto
doaj   +1 more source

Ternary relative velocity; astonishing conflict of the Lorentz group with relativity [PDF]

open access: yesarXiv, 2011
We are proving that the Lorentz boost entails the relative velocity to be ternary: ternary relative velocity is a velocity of a body with respect to an interior observer as seen by a preferred exterior-observer. The Lorentz boosts imply non-associative addition of ternary relative velocities.
arxiv  

Molecular imaging predicts trastuzumab‐deruxtecan (T‐DXd) response in head and neck cancer xenograft models

open access: yesMolecular Oncology, EarlyView.
Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed   +8 more
wiley   +1 more source

On the rational relationship between Heisenberg principle and general relativity [PDF]

open access: yesarXiv, 2006
The research shows that the Heisenberg principle is the logic results of general relativity principle. If inertia coordinator system is used, the general relativity will logically be derived from the Heisenberg principle. The intrinsic relation between the quantum mechanics and general relativity is broken by introducing pure-imaginary time to explain ...
arxiv  

Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma

open access: yesMolecular Oncology, EarlyView.
GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski   +19 more
wiley   +1 more source

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