Generalized, Energy-conserving Numerical Simulations of Particles in General Relativity. I. Time-like and Null Geodesics [PDF]
, 2018 Fabio Bacchini +3 more
openalex +1 more source
Towards Unification of General Relativity and Quantum Theory: Dendrogram Representation of the Event-Universe. [PDF]
Entropy (Basel), 2022 Shor O, Benninger F, Khrennikov A.
europepmc +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Hamiltonian analysis of general relativity and extended gravity from the iterative Faddeev-Jackiw symplectic approach [PDF]
, 2018 Davi C. Rodrigues +2 more
openalex +1 more source
Geometry of static w = - 1 / 5 perfect fluid spheres in general relativity. [PDF]
Eur Phys J C Part Fields, 2022 Fazlpour B, Banijamali A, Faraoni V.
europepmc +1 more source
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Nonlocal teleparallel cosmology
European Physical Journal C: Particles and Fields, 2017 Even though it is not possible to differentiate general relativity from teleparallel gravity using classical experiments, it could be possible to discriminate between them by quantum gravitational effects. These effects have motivated the introduction of
Sebastian Bahamonde +3 more
doaj +1 more source
Black hole binary OJ287 as a testing platform for general relativity [PDF]
, 2014 M. J. Valtonen +4 more
openalex +1 more source
The Principle of Covariance and the Hamiltonian Formulation of General Relativity. [PDF]
Entropy (Basel), 2021 Tessarotto M, Cremaschini C.
europepmc +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source