Results 131 to 140 of about 22,988 (314)
FEBS Open Bio, EarlyView.KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani +6 more
wiley +1 more source
FEBS Open Bio, EarlyView.Aged human bmMSCs are seeded in the scaffold. Osteoblastic induction can slightly increase cell's bone‐forming activity to produce bone‐like tissues, shown as the sporadic xylenol orange‐stained spots (the lower left image). Notably, pioglitazone plus EGCG co‐treatment dramatically increases cell's bone‐forming activity and bone‐like tissue production (
Ching‐Yun Chen +6 more
wiley +1 more source
Horizon phase spaces in general relativity
Journal of High Energy PhysicsWe derive a prescription for the phase space of general relativity on two intersecting null surfaces using the null initial value formulation. The phase space allows generic smooth initial data, and the corresponding boundary symmetry group is the ...
Venkatesa Chandrasekaran +1 more
doaj +1 more source
A Note on the Axisymmetric Stationary Metric in the General Theory of Relativity [PDF]
, 2019 Tetu Makino
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FEBS Open Bio, EarlyView.dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon +6 more
wiley +1 more source
Quantum Gravity in Everyday Life: General Relativity as an Effective Field Theory
Living Reviews in Relativity, 2004 This article is meant as a summary and introduction to the ideas of effective field theory as applied to gravitational systems, ideas which provide the theoretical foundations for the modern use of general relativity as a theory from which precise ...
Burgess Cliff P.
doaj
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Cognitive impairment (CI) affects the quality of life in multiple sclerosis (MS). Identifying influencing factors is key to improving CI monitoring. This systematic review and meta‐analysis examines clinical and sociodemographic variables impacting the cognitive screening Symbol Digit Modalities Test (SDMT) performance across MS ...
Katalin Lugosi +8 more
wiley +1 more source
Perturbative Quantum Gravity and its Relation to Gauge Theory
Living Reviews in Relativity, 2002 In this review we describe a non-trivial relationship between perturbative gauge theory and gravity scattering amplitudes. At the semi-classical or tree-level, the scattering amplitudes of gravity theories in flat space can be expressed as a sum of ...
Bern Zvi
doaj
A Gaussian Process Framework for Testing General Relativity with Gravitational Waves
The Astrophysical JournalGravitational-wave astronomy provides a promising avenue for the discovery of new physics beyond general relativity as it probes extreme curvature and ultrarelativistic dynamics.
Lachlan Passenger +5 more
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NR4A1 Exerts Pro‐Tumor Role in Glioblastoma via Inducing xCT/GPX4‐Regulated Ferroptosis
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Purpose This study investigates NR4A1's paradoxical roles in glioblastoma (GBM) progression, focusing on its mechanistic link to ferroptosis regulation. We aimed to resolve conflicting reports of NR4A1 as both an oncogene and a tumor suppressor by defining its transcriptional control over xCT/GPX4‐mediated iron homeostasis and its clinical ...
Peng Tao +10 more
wiley +1 more source