Optimizing photoexcitation conditions for time‐resolved X‐ray solution scattering experiments
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering (TR‐XSS) is a powerful technique to visualize how proteins change their structure in real time after light activation. Selecting the right laser photoexcitation conditions—fluence, excitation geometry, and sample refresh rate—is critical to maximize the experimental signal while avoiding unwanted side effects ...
Matteo Levantino
wiley +1 more source
On Thermodynamical Kluitenberg Theory in General Relativity. [PDF]
Entropy (Basel)Farsaci F, Rogolino P.
europepmc +1 more source
Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound
FEBS Open Bio, EarlyView.We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda +4 more
wiley +1 more source
Black Holes as Laboratories: Tests of General Relativity. [PDF]
Gen Relativ GravitGregory R, Nissanke S.
europepmc +1 more source
Maxwell's Demon and the Problem of Observers in General Relativity. [PDF]
Entropy (Basel), 2018 Herrera L.
europepmc +1 more source
FEBS Open Bio, EarlyView.Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty +13 more
wiley +1 more source
At the interface of asymptotics, conformal methods and analysis in general relativity. [PDF]
Philos Trans A Math Phys Eng SciTaujanskas G, Valiente Kroon JA.
europepmc +1 more source
Mapping nonlinear gravity into General Relativity with nonlinear electrodynamics. [PDF]
Eur Phys J C Part Fields, 2018 Afonso VI +3 more
europepmc +1 more source
Dual native G‐quadruplex folding is associated with chromatin looping at the MYC locus
FEBS Open Bio, EarlyView.BG4‐detectable G‐quadruplex (G4) in HaCaT and NHEK keratinocytes identified folded and unfolded G4s enriched at promoters/TSSs and active enhancers, whereas unfolded G4s also overlapped weak/poised enhancers. At MYC–PVT1, 3C‐qPCR detected enhancer–promoter looping only when G4s were simultaneously folded at both regulatory elements under native ...
Dieila Giomo de Lima +7 more
wiley +1 more source
From conformal infinity to equations of motion: conserved quantities in general relativity. [PDF]
Philos Trans A Math Phys Eng SciPenrose R.
europepmc +1 more source