Results 181 to 190 of about 10,399,375 (306)
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill +6 more
wiley +1 more source
General relativity: basic ideas and observables
This stet of lectures will review the basic ideas and techniques of the present "standard" description of gravity (i.e. general relativity). A few examples of the applications of general relativity to the description of the macroscopic world will be ...
Damour, Thibault Marie Alban Guillaume
core
Yeast Gcn2 retains activity following humanization of its auto‐phosphorylation region
Using Saccharomyces cerevisiae as a model to study Gcn2 activation and regulation is limited by the lack of antibodies detecting phosphorylated Gcn2. To overcome this, we engineered Gcn2‐HsC, a yeast Gcn2 variant recognizable by commercial anti‐human phospho‐GCN2 antibodies.
Reuben A. Anderson +2 more
wiley +1 more source
Magnetohydrodynamic simulations of binary neutron star mergers in general relativity: Effects of magnetic field orientation on jet launching. [PDF]
Ruiz M, Tsokaros A, Shapiro SL.
europepmc +1 more source
General relativity and gravitational waves
An internationally famous physicist and electrical engineer, the author of this text was a pioneer in the investigation of gravitational waves.
Weber, Johanna
core
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas +6 more
wiley +1 more source
Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito +7 more
wiley +1 more source
Relativity: the special and the general theory
After completing the final version of his general theory of relativity in November 1915, Albert Einstein wrote a book about relativity for a popular audience. His intention was "to give an exact insight into the theory of relativity to those readers who,
Einstein, Albert
core
KDAC6 has been associated with cell motility and actin structures, but specific domain contributions are not established. The two catalytic domains have differential effects on motility and F‐actin regulation, affecting cortical F‐actin density, motility, stress fibers, and cell spreading.
Taylor V. Joseph +7 more
wiley +1 more source
Master field equations for spherically symmetric gravitational fields beyond general relativity. [PDF]
Carballo-Rubio R.
europepmc +1 more source

